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OpenTrials
Completed

NCT Number: NCT02568371

Biobank Based on the i-Share Student Cohort

The bio-Share project aims at collecting blood samples in students participating in the i-Share cohort (www.i-share.fr). Investigators aim at setting up a platform that will enable investigators in the future to study biological determinants of conditions that affect young adults and to test certain hypotheses on the pathophysiology and mechanisms underlying diseases occurring both at a young age and later in life (as early exposures may also impact late onset diseases)

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Key information

Conditions

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Centre Hospitalier Universitaire de Bordeaux - PELLEGRIN

Bordeaux, Aquitaine, France

About this study

The i-Share cohort was set up to study various important aspects of students' health and to better understand early mechanisms contributing to the occurrence of common diseases representing an important public health burden. The i-Share cohort is funded by an "investment for the future grant" from the French National Research Agency (ANR-10-COHO-05-01) with the aim to recruit 30000 students at the University of Bordeaux, and a few additional partner universities in France and abroad (www.i-share.fr).

The bio-Share study is a biological repository embedded within the i-Share study, aiming at collecting blood samples (for genetic analyses as well as measurement of other biomarkers) from a subset of 2000 i-Share participants volunteering for this ancillary project.

The goal is to set up a platform that will enable investigators in the future to study biological determinants of conditions that affect young adults and to test certain hypotheses on the pathophysiology and mechanisms underlying diseases occurring both at a young age and later in life (as early exposures may also impact late onset diseases).

The biobank will comprise the following biological materials: plasma, serum, whole blood, red blood cells, DNA, RNA. Levels of fasting glucose and lipid levels (total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides) will be returned to participants.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Be an i-Share participant in Bordeaux
  • Being aged 18 years or more
  • Being affiliated or beneficiary of a social security
  • Having filled out the first online i-Share questionnaire
  • Having signed a written informed consent

Exclusion criteria

  • Pregnant or breastfeeding women,
  • Persons who cannot personally give their consent and adults under guardianship.

Treatment and study plan

Primary outcomes

  1. The acquisition date of blood samples

    Time frame: Day 1

  2. The number of the aliquots for each of the stored biological samples

    Time frame: Day 1

  3. The total volume of the aliquots for each of the stored biological samples

    Time frame: Day 1

Secondary outcomes

  1. Glucose (fasting)

    Time frame: Day 1

  2. Total cholesterol (fasting)

    Time frame: Day 1

  3. High-density lipoprotein cholesterol (fasting)

    Time frame: Day 1

  4. Low-density lipoprotein-cholesterol (fasting)

    Time frame: Day 1

  5. Triglycerides (fasting)

    Time frame: Day 1

Sponsors and collaborators

Lead sponsor

University Hospital, Bordeaux

Other

Collaborators

  • National Research Agency, France

Registry information

Acronym: bio-Share

Important dates

Study start
2015
Primary completion
2017
Study completion
2017
First posted
Oct 5, 2015
Registry last updated
Mar 18, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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