Education and Health Sciences
Limerick, V94 T9PX, Ireland
NCT Number: NCT04872530
This study aims to inform of the mechanism of action of plant-based protein by measuring the bioavailability (i.e. rate of appearance and magnitude of concentration in the circulation following oral ingestion) of key amino acid and metabolic products that regulate skeletal muscle protein synthesis (MPS) in humans.
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Notify Me18 year–35 year
Male
Interventional
Not applicable
Limerick, V94 T9PX, Ireland
Plant-based proteins contain several amino acids that are essential to signal muscle growth/repair and act as a substrate during muscle protein synthesis. However, compared to animal protein or free-amino acids, the bioavailability of certain essential amino acids may be compromised. Following selective processing (e.g. removal of carbohydrate and/or other anti-nutritive factors) food grade plant-based protein concentrates possibly confer greater bioavailability and bioactivity in vivo. This project explores the bioavailability and bioactivity of selected plant-based protein concentrates following oral ingestion in young, healthy men and women.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Pea-protein concentrate
Fava-bean protein concentrate
Chickpea protein concentrate
Red lentil protein concentrate
Non-essential amino acid blend
Whey protein concentrate
Time frame: 3 hours
Plasma amino acids measured by HPLC
University of Limerick
Other
Bioavailability of Amino Acids and Metabolic Products Following Oral Ingestion of Plant-Based Proteins in Young, Healthy Men and Women Aged 18-35y
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