Billroth II reconstruction
ProcedureBillroth II reconstruction, in which a loop of jejunum is mobilized and anastomosed to the gastric remnant
NCT Number: NCT06229197
The primary aim of this trial is to rigorously evaluate the comparative benefits and potential risks associated with Billroth II reconstruction with Braun anastomosis versus Billroth II reconstruction alone following distal gastrectomy with D2 lymphadenectomy in patients diagnosed with gastric cancer. This assessment focuses on delineating the therapeutic efficacy, safety profile, and overall clinical outcomes of these two surgical approaches in treating this condition.
Trial opening soon.
Get Notified18 year–80 year
All sexes
Interventional
Not applicable
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
To be enrolled, participants must be phase I-III patients with initial treatment of radical distal gastrectomy and satisfying the following inclusion criteria:
Exclusion criteria
Patients will be excluded according to the following criteria:
Billroth II reconstruction, in which a loop of jejunum is mobilized and anastomosed to the gastric remnant
This is an additional surgical connection (anastomosis) created between two parts of the small intestine, specifically between the afferent (incoming) and efferent (outgoing) limbs of the jejunum near the gastrojejunostomy (the new connection between the stomach and small intestine created during a Billroth II procedure).
Time frame: 6 months, 12 months
by endoscopic evaluation
Time frame: 6 months, 12 months
The preoperative and postoperative QoL of patients between the two groups.
Time frame: 6 months, 12 months
Changes in body weight (kg) or BMI from baseline
Time frame: within 30 days after surgery
Time taken to pass first stool or flatus
Time frame: within 30 days after surgery
e.g., anastomotic leakage, anastomotic bleeding assessed by laboratory test in combination with clinical features, radiological diagnostic methods, endoscopy, diagnostic laparoscopy.
Time frame: 6 months, 12 months
e.g., food residue and bile reflux (assessed according to the RGB classification).
Contact information is provided by the study sponsor or research team.
Sichuan University
Other
Billroth II With Braun Anastomosis Versus Billroth II Anastomosis After Radical Distal Gastrectomy With D2 Lymphadenectomy for Gastric Cancer: a Randomized Controlled Trial
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07314203
Digestive System Diseases, Digestive System Neoplasms
Fuzhou, Fujian, China
View Trial DetailsNCT04677673
Chemotherapy Effect, Digestive System Diseases
View Trial DetailsNCT04168346
Anemia, Anemia, Hypochromic
View Trial DetailsNCT06464978
Anastomotic Leak, Anastomotic Leakage
Nanchong, Sichuan, China
View Trial Details