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OpenTrials
Enrolling by Invitation

NCT Number: NCT06808321

Benidipine in Hypertensive and/or Chronic Coronary Syndrome Patients

Evaluation of the clinical outcomes of Benidipine initiated by physician's preference in patients with hypertension and/or angina pectoris (chronic coronary syndrome) presenting to cardiology outpatient clinics in Turkey.

Enrolling by Invitation

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Key information

About this study

  • Benidipine is a dihydropyridine calcium channel blocker used in the treatment of hypertension and angina pectoris. There are currently no large-scale observational studies in these patient groups in Turkey.
  • There is no record of benidipine in clinicaltrials.gov, which is an important database especially for the registration of drug and interventional studies.
  • Therefore, it will be extremely important to include this study in clinicaltrials.gov and to evaluate the clinical efficacy of Bendipine in patients with hypertensive and/or angina pectoris in 7 geographical regions of Turkey.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with hypertension and/or angina pectoris on the background of chronic coronary syndrome who have been receiving Benidipine treatment for at least 1 month and will continue to receive Benidipine treatment
  • Male or female outpatients, 18-80 years of age
  • Patients with mild to moderate essential hypertension who have been receiving or will continue Benidipine treatment for at least 1 month
  • Outpatients with clinically stable angina pectoris and patients who have been receiving or will continue Benidipine treatment for at least 1 month
  • Those who signed the written informed consent form

Exclusion criteria

  • Patients with secondary hypertension
  • Emergency hypertensive patients
  • Having to take other medications during the study that may affect blood pressure
  • Allergic to DHP calcium antagonists
  • Evidence of decompensated congestive heart failure, unstable angina or severe arrhythmia
  • Severe renal or hepatic dysfunction
  • Pregnant or lactating women
  • Participation in other clinical trials within 3 months prior to this study
  • Patients who did not sign the consent form of the study

Treatment and study plan

Benidipine Hydrochloride

Drug

The safety and efficacy of a dihydropyridine calcium channel blocker for the treatment of high blood pressure and/or angina pectoris

Primary outcomes

  1. The Percentage of Patients Achieving Target Sitting Blood Pressure of Less Than 130/85

    Time frame: 3 months

  2. Change in angina symptom severity as measured by the Seattle Angina Questionnaire score from baseline to the end of study

    Time frame: 3 months

Sponsors and collaborators

Lead sponsor

The Society of Prevention and Awareness of Cardiovascular Diseases

Other

Registry information

Official study title

Evaluation of Clinical Outcomes of Benidipine in Hypertensive and/or Chronic Coronary Syndrome Patients in the Turkish Population

Acronym: Benidipine-TR

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Feb 5, 2025
Registry last updated
Sep 9, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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