Beijing Vascular Disease Patients Evaluation STudy

This study aimed to establish vascular disease early detection system and scoring systems by comprehensive vascular disease risk factors and vascular function evaluation index. And prevention of vascular-related diseases, high-risk groups through positive lifestyle changes: such as lipid-lowering, smoking cessation, reversing early vascular lesions, to avoid end-stage vascular events.

• Detection of vascular function indicators include: PWV, IMT, CFVR, FMD, CAVI, ABI, LDL-C, HOMA-IR, hs-CRP, Hcy, BNP, UA and so on.
• Design the questionnaire: surveying the lifestyle, personal history, family history of the study population.
• Follow-up:2 years of observation, recording the end time of vascular events, including cardiovascular events (acute myocardial infarction, angina, coronary reperfusion therapy), stroke, heart failure, peripheral vascular disease.
• Statistics: Complex the factors of vascular disease, screen for an effective indicator to predict cardiovascular events, and based on the weight of the different factors, the establish the rating system, use the system to predict the incidence of vascular events terminal, and compare the system with the previous scoring system such as FRS (Framingham Risk Score).

Inclusion criteria

• health subjects with or without history of vascular-related diseases; or
• hypertension subjects; or
• diabetes mellitus subjects; or
• coronary artery disease; or
• cerebrovascular disease;or
• hyperlipidemia subjects.

Exclusion criteria

• severe infectious diseases and inflammatory diseases;
• liver and kidney failure;
• cancer;
• immunological diseases;
• hematological system diseases。