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OpenTrials
Completed

NCT Number: NCT05010291

Behavioural Text Messages to Improve Retention in Care in South Africa

The proportion of South Africans aware of their HIV status and on treatment remains lower than optimal. The goal of this study is to rapidly determine whether text messages framed according to behavioural economics principles increase clinic attendance among recipients of care on antiretroviral therapy in South Africa. We hypothesize that messages incorporating behavioural economics principles will increase the likelihood of recipients of care attending clinic appointments and returning within 28 days of a missed appointment.

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Key information

About this study

The objective of this study is to rapidly determine whether text messages framed according to behavioural economics principles increase the likelihood that recipients of care attend their clinic appointment and return to clinic within 28 days of a missed appointment. The study will be nested in a routine HIV program, in approximately 5 selected Aurum Institute clinics based in Ekurhuleni district, Gauteng province, South Africa.

Intervention arms will include voice call attempts and one-way text messages sent by clinic staff to recipients of care in two scenarios: 1) Approximately 3-7 days in advance of a clinic appointment for collecting antiretroviral medication supplies or collection of a specimen for viral load testing and 2) Approximately 24 hours after a missed clinic appointment.

This individually randomised trial will have four arms. Each time there is an upcoming or missed clinic visit clinic staff will randomly assign recipients of care to one of the following study arms: 1) Standard of Care 2) Loss aversion framed messaging 3) Social norms framed messaging or 4) Altruism framed messaging.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Registered to receive ART (this includes patients receiving ART through multi-month scripting) at selected study sites.
  • Aged ≥18 years.
  • Have a documented cell phone number in their clinic records
  • Are eligible to receive appointment reminders as part of routine care OR eligible to receive follow-up text messages as part of routine care for missed clinic appointments.

Exclusion criteria

  • Do not have contact details in their clinic records.
  • Have contact details on record that are established to belong to someone else upon follow-up (i.e., wrong number).
  • Have contact details that are deactivated/non-functional (i.e., voice notification that the number does not exist).
  • Are documented to have self-transferred out of the clinic.
  • Are known to have been deceased.

Treatment and study plan

Standard of Care (SOC) text message reminder to attend clinic appointment

Behavioral

SOC one-way text message reminding recipient of care to either 1) attend a scheduled clinic appointment or 2) visit the clinic after a missed appointment.

Loss aversion framed text message reminder to attend clinic appointment

Behavioral

Loss aversion framed one-way text message reminding recipient of care to either 1) attend a scheduled clinic appointment or 2) visit the clinic after a missed appointment.

Social norms framed text message reminder to attend clinic appointment

Behavioral

Social norms framed one-way text message reminding recipient of care to either 1) attend a scheduled clinic appointment or 2) visit the clinic after a missed appointment.

Altruism framed text message reminder to attend clinic appointment

Behavioral

Altruism framed one-way text message reminding recipient of care to either 1) attend a scheduled clinic appointment or 2) visit the clinic after a missed appointment.

Primary outcomes

  1. Appointment reminders

    Time frame: Approximately 3-5 months

    Proportion of clients with schedule clinic visit attendance, defined as the number of patients with a verified clinic on the scheduled appointment day/the total number of clients that were sent appointment reminders (stratified by study arm).

  2. Missed clinic appointments

    Time frame: Approximately 3-5 months

    Proportion of patients with a verified clinic visit within 28 days of missing a scheduled clinic appointment defined as the number of patients with a verified clinic within 28 days of missing a scheduled clinic appointment/the total number of clients that Tracers sent text messages following a missed clinic appointment.

Sponsors and collaborators

Lead sponsor

University of Pennsylvania

Other

Collaborators

  • Aurum Institute
  • University of Witwatersrand, South Africa

Registry information

Official study title

Behavioural Text Messaging to Improve Retention in Care for Patients on Antiretroviral Therapy in Ekurhuleni District, South Africa

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Aug 18, 2021
Registry last updated
Jul 20, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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