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NCT Number: NCT07725250

Behavioral Interventions Combining AI/ML and Personalized Medicine to Reduce Cardiovascular Risk - Randomized Controlled Trial

This study evaluates a new digital health program that uses artificial intelligence (AI) to help patients lower their blood pressure through personalized lifestyle recommendations. The program collects information about patients' daily habits and blood pressure readings, then uses AI to suggest lifestyle changes that may work best for each person. The study will measure how well this program works across different groups of patients and aims to improve the program design to make it more effective and easier to use. The program will be offered to diverse patients at UC San Diego Health, including people of different ages, genders, races/ethnicities, and economic backgrounds, as part of their regular healthcare services.

Recruiting

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Key information

Conditions

Hypertension Cardiovascular Diseases Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Stage I-II hypertension (average clinical readings of blood pressure over 140/90)
  • Adequate decisional capacity to make a choice about participating in this research study
  • Fully ambulatory (not requiring assistive device such as a cane, wheelchair, walker, etc.)

Exclusion criteria

  • Pregnancy
  • Under age 18 years
  • Institutionalized individuals who are likely to be vulnerable
  • Dependent on supplemental oxygen

Treatment and study plan

Digital heath tool

Other

Digital health tool of patient-tailored lifestyle recommendations for blood pressure maintenance. Current "simplified" remote patient monitoring program referred to as "P1000." Requires daily blood pressure readings only.

Low-intensity recommendation

Other

AI-enhanced lifestyle and health recommendations provided weekly. This requires blood pressure readings, as well as passive readings, (e.g. sleep, movement), and a daily questionnaire.

High-intensity recommendation

Other

AI-enhanced lifestyle and health recommendations provided weekly, plus daily reminders. This requires blood pressure readings, as well as passive readings, (e.g. sleep, movement), and a daily questionnaire.

Primary outcomes

  1. Systolic blood pressure measurement

    Time frame: 6 months

Study contacts

Contact information is provided by the study sponsor or research team.

Amanda Walker

CONTACT

[email protected]

617-588-1445

Ross Graham

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

National Bureau of Economic Research, Inc.

Other

Collaborators

  • National Institute on Aging (NIA)
  • University of California, San Diego

Registry information

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Jul 24, 2026
Registry last updated
Jul 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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