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OpenTrials
Completed

NCT Number: NCT06456788

Barriers and Facilitators to MMR Vaccination Among Healthcare Workers

Measles is a highly contagious disease which can result in severe complications in some patients. Healthcare workers have a higher risk of getting measles than the general population because of their increased risk of exposure from patients with measles attending hospitals. Having had measles in the past or at least one dose of the measles, mumps and rubella (MMR) vaccine provides protection (immunity) against measles. UK government guidelines therefore recommend that healthcare workers and non-clinical staff with direct patient contact are fully vaccinated or have other evidence of immunity. Yet, evidence from recent measles outbreaks suggests that some healthcare workers are not immune or do not know if they are immune, with implications for containment efforts, cost and transmission. The purpose of this study is to identify barriers and facilitators to uptake of the MMR vaccine among healthcare workers at King's College Hospital NHS Foundation Trust (KCH). KCH healthcare workers will be eligible to take part in the study if they are aged 18 and over and have direct contact with patients. In addition, the research will focus on four subgroups of healthcare workers at KCH: those who are not immune, those who have not completed the full vaccination schedule, those who don't know their immunity status, those received the vaccine only after joining KCH. The latter may provide insights into facilitators to vaccine uptake. Measles immunity forms part of the occupational health screening at KCH. A series of semi structured interviews lasting approximately 1 hour will explore participants' experiences of the occupational health vaccine screening process and measles vaccine campaigns at KCH; why they are unvaccinated/not fully vaccinated/do not know if they are immune/decided to be vaccinated after joining KCH; and what measures or interventions may help healthcare workers when deciding whether to get the MMR vaccine.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

King's College London

London, United Kingdom

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Are aged 18 and over
  • Currently work as a healthcare worker at the Trust
  • Have direct contact with patients
  • Don't know if they have had measles and don't know if they have been vaccinated
  • Or: Have not had measles and have not received the MMR vaccine
  • Or: Have only received 1 dose of the MMR vaccine
  • Or: Received the MMR vaccine after joining the Trust

Exclusion criteria

  • Are aged <18 years old
  • Work in a role at the Trust that does not involve direct contact with patients (e.g., administrative or business staff)
  • Are sure and/or have evidence that they have had measles in the past or both doses of the MMR vaccine before joining the Trust
  • Are not able to give informed consent

Treatment and study plan

MMR vaccination

Biological

MMR vaccination status

Primary outcomes

  1. Barriers to MMR vaccination

    Time frame: Collected at one timepoint 1 day during qualitative interview

    Barriers to MMR vaccination will be explored in the qualitative interview

  2. Facilitators to MMR vaccination

    Time frame: Collected at one timepoint 1 day during qualitative interview

    Facilitators to MMR vaccination will be explored in the qualitative interview

  3. Reasons for not knowing immunity status

    Time frame: Collected at one timepoint 1 day during qualitative interview

    Reasons for not knowing immunity status will be explored in the qualitative interview

Secondary outcomes

  1. Experiences of the occupational health vaccine screening process at KCH

    Time frame: Collected at one timepoint 1 day during qualitative interview

    Experiences of the occupational health vaccine screening process at the Trust will be explored in the qualitative interview

Sponsors and collaborators

Lead sponsor

King's College London

Other

Collaborators

  • King's College Hospital NHS Trust
  • UK Health Security Agency

Registry information

Official study title

Exploring Barriers and Facilitators to Uptake of the MMR Vaccine Among Healthcare Workers at King's College Hospital NHS Foundation Trust

Acronym: BFMMRHCW

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Jun 13, 2024
Registry last updated
May 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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