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Completed

NCT Number: NCT01581190

Bananas as an Energy Source During Exercise: a Metabolomics Approach

This study compared the acute effect of ingesting bananas (BAN) versus a 6% carbohydrate drink (CHO) on 75-km cycling performance and post-exercise inflammation, oxidative stress, and innate immune function using traditional and metabolomics-based profiling.

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Key information

Conditions

Intense Exercise Behavior Inflammation Motor Activity Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year–45 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Human Performance Lab, North Carolina Research Campus

Kannapolis, North Carolina, 28081, United States

About this study

Trained cyclists (N=14) completed two 75-km cycling time trials (randomized, crossover) while ingesting BAN or CHO (0.2 g/kg carbohydrate every 15 min). Pre-, post-, and 1-h-post-exercise blood samples were analyzed for glucose, granulocyte (GR) and monocyte (MO) phagocytosis (PHAG) and oxidative burst activity, nine cytokines, F2-isoprostanes, ferric reducing ability of plasma (FRAP), and metabolic profiles using gas chromatography-mass spectrometry.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male
  • Ages 18-45 years
  • Cyclists, road racing experience.
  • Willing to avoid the use of supplements, herbs, medications during the study.

Exclusion criteria

  • Female
  • Over the age of 45 years
  • No cycling racing experience
  • Using supplements and medications during the study

Treatment and study plan

Bananas versus 6% carbohydrate beverage

Dietary Supplement

Trained cyclists (N=14) completed two 75-km cycling time trials (randomized, crossover) while ingesting BAN or CHO (0.2 g/kg carbohydrate every 15 min).

Other names: Gatorade

Primary outcomes

  1. Performance and fuel substrate utilization as measured through metabolomics

    Time frame: Up to 6 months

    Will measure shifts in metabolites following 75-km cycling while ingesting bananas or 6% carbohydrate beverage. The shift in metabolites will be assessed using GC-MS. Time frame from date of randomization until the last samples are collected and analyzed will be up to six months.

Secondary outcomes

  1. Exercise-induced inflammation.

    Time frame: up to 6 months

    Cytokine panel (IL-6, IL-8, IL-10, TNF-alpha) before and after cycling 75-km; measured with Meso Scale Discovery in pg/ml. Time frame from randomization until the last samples are collected and analyzed will be up to six months.

Sponsors and collaborators

Lead sponsor

Appalachian State University

Other

Collaborators

  • Dole Food Company

Registry information

Official study title

Comparison of Bananas and Gatorade on Performance and Exercise-induced Inflammation, Oxidative Stress, and Changes in Immune Function in Endurance Athletes

Important dates

Study start
2011
Primary completion
2011
Study completion
2011
First posted
Apr 20, 2012
Registry last updated
Apr 20, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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