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Completed

NCT Number: NCT00609700

Balanced Volume Replacement Therapy With Ringer's Acetate Solution in Burn Injury

This observational study compares the influence of Ringer's Lactate solution and Ringer's Acetate solution on organ function scores following severe burn injury.

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Key information

Conditions

Severe Burn Injury Burns Wounds and Injuries

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Klinikum St Georg

Leipzig, Saxony, 04129, Germany

About this study

In the early period following severe burn injury volume replacement with high amounts of crystalloids is necessary. In this study we compare the organ function scores of a historical patient group, treated with Ringer's Lactate solution, with an actual patient population, treated with Ringer's Acetate solution.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age >=18 years and <80years
  • Burned surface area >20% and <70%
  • Burn injury < 24 hours
  • Agreement to the study procedures

Exclusion criteria

  • Burned surface area > 70%
  • Expected survival time < 24 hours
  • Acute or chronic heart failure NYHA III or IV
  • Adult respiratory distress syndrome
  • Renal failure
  • Hepatic failure

Treatment and study plan

Primary outcomes

  1. Change of SOFA-score from day 3 to day 7 after severe burn injury

    Time frame: day3, day7, day28, day60

Secondary outcomes

  1. Changes in electrolyte-balance

    Time frame: day3, day7, day28

Sponsors and collaborators

Lead sponsor

Klinikum St. Georg gGmbH

Other

Registry information

Acronym: VoLTRAB

Important dates

Study start
2007
Primary completion
2010
Study completion
2010
First posted
Feb 7, 2008
Registry last updated
Oct 17, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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