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Completed

NCT Number: NCT00082485

Baclofen for the Treatment of Cocaine Dependence - 1

The purpose of this study is to assess the efficacy and safety of baclofen for the treatment of cocaine dependence.

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Key information

Conditions

Cocaine-Related Disorders Chemically-Induced Disorders Mental Disorders Substance-Related Disorders

Age range

18 year–99 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

San Francisco General Hosptial, San Francisco, California, United States

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About this study

Double-blind, placebo-controlled, parallel design trial of baclofen for the treatment of cocaine dependence

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Subject must have DSM-IV diagnosis of cocaine dependence.
  • Subject must be seeking treatment for cocaine dependence.
  • Be be able to verbalize understanding of consent form, provide written consent and verbalize willingness to complete study procedures.

Exclusion criteria

  • Please contact site for more information.

Treatment and study plan

Baclofen

Drug

Dose escalation 10-60mg (week 1) 60 mg (weeks 2-7) Dose taper (week 8)

Placebo

Other

Placebo

Primary outcomes

  1. Effects of medication on cocaine craving

Sponsors and collaborators

Lead sponsor

National Institute on Drug Abuse (NIDA)

Nih

Registry information

Official study title

Multi-Center Trial of Baclofen for the Treatment of Cocaine Dependence

Important dates

Study start
2004
Primary completion
2006
First posted
May 12, 2004
Registry last updated
Jan 12, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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