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NCT Number: NCT06850662

Backward Walking Observation Training in People With Stroke and Gait Quality in Stroke

Walking impairment is one of the most common and concerning issues for individuals with stroke. Previous studies have often used improvements in walking speed and distance as reference indicators for gait performance progress in individuals with stroke. However, for people with chronic stroke, it may be more appropriate to prioritize improving gait symmetry and gait variability to enhance gait quality as a primary intervention goal. Additionally, stroke can lead to an imbalance in interhemispheric brain activity, which evolves as motor function recovers. According to the literature review, backward walking may extend the support time of the lower limbs, thereby enhancing the weight-bearing capacity of the affected limb. This, in turn, could promote gait symmetry and reduce gait variability. Changes in brain activity might also accompany such improvements in gait quality. Therefore, this study aims to investigate the immediate, short-term and post carryover intervention effects of backward walking observation training on gait quality in individuals with chronic stroke as well as to explore its effects on interhemispheric activity balance in individuals with chronic stroke.

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Key information

Age range

20 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University

Taipei, 112, Taiwan

Location status: Recruiting

Location contact

Yea-Ru Yang, PhD

CONTACT

[email protected]

+886-2-2826-7279

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ≥ 6 months after the diagnosis of stroke
  • Independent walking over at least 7m with or without a walking aid
  • Mini-mental state examination score ≥ 24

Exclusion criteria

  • Had difficulty in backward walking
  • Any neuromuscular disorders history
  • With visual or auditory disorders
  • Unstable cardiac status or uncontrolled hypertension
  • Any musculoskeletal disorders that would affect walking ability

Treatment and study plan

Backward walking observation training

Other

Backward treadmill training after watching a video of backward walking.

Non-motor observational backward walking training

Other

Backward treadmill training after watching a video of landscape without any movements.

Primary outcomes

  1. Brain activity

    Time frame: Baseline, 4 weeks after training, and 4-week follow-up

    Using functional near infrared spectroscopy to measure the oxygenated hemoglobin (HbO) and deoxygenated hemoglobin (HbR) in the bilateral prefrontal cortex, supplementary motor area and primary motor cortex.

  2. Gait symmetry

    Time frame: Baseline, post-intervention, 4 weeks after training, and 4-week follow-up

    Using GAITRite system to measure the symmetry of spatiotemporal parameters

  3. Gait varability

    Time frame: Baseline, post-intervention, 4 weeks after training, and 4-week follow-up

    Using GAITRite system to measure the coefficient of variation of spatiotemporal parameters

Secondary outcomes

  1. Gait performance

    Time frame: Baseline, post-intervention, 4 weeks after training, and 4-week follow-up

    Using GAITRite system to measure the gait spatiotemporal parameters

  2. Time Up & Go test

    Time frame: Baseline, 4 weeks after training, and 4-week follow-up

    Using Time Up & Go test to assess functional mobility

  3. Activities-specific Balance Confidence Scale

    Time frame: Baseline, 4 weeks after training, and 4-week follow-up

    Using Activities-specific Balance Confidence Scale to evaluate individual's balance confidence in performing daily activities

  4. Taiwan Chinese version Falls Efficacy Scale

    Time frame: Baseline, 4 weeks after training, and 4-week follow-up

    Using Taiwan Chinese version Falls Efficacy Scale to evaluate concerns about falling

Study contacts

Contact information is provided by the study sponsor or research team.

Yea-Ru Yang, PhD

CONTACT

[email protected]

+886228267279

Sponsors and collaborators

Lead sponsor

National Yang Ming Chiao Tung University

Other

Registry information

Official study title

The Effect of Backward Walking Observation Training on Improving Brain Activity and Gait Quality in People With Stroke

Important dates

Study start
2025
Primary completion
2028
Study completion
2028
First posted
Feb 27, 2025
Registry last updated
Jun 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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