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NCT Number: NCT07467031

Bachstim Registry: a Feasability Study of Bachmann's Area Pacing

During pacemaker implantation, the atrial lead is commonly positioned in the right atrium. However, this pacing location can be problematic because it may disrupt physiological atrial activation, leading to atrial dyssynchrony. Such dyssynchrony has been associated with an increased risk of atrial fibrillation and its related complications.

To mitigate atrial dyssynchrony, pacing of the Bachmann's bundle region has emerged as an alternative strategy. Bachmann's bundle is the principal interatrial conduction pathway, and pacing at this site may help preserve physiological atrial activation. Several studies have suggested that pacing in this region can significantly reduce the incidence of new-onset atrial fibrillation and heart failure in selected populations.

To date, however, robust data from large cohorts regarding the feasibility of Bachmann's bundle area pacing and the factors associated with successful implantation remain limited. To address this gap, we established the Bachstim cohort study, aimed at determining the success rate of Bachmann's bundle area pacing and identifying the clinical and procedural factors associated with its feasibility.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Cardiac pacemaker with atrial lead indication

Exclusion criteria

  • patients < 18 years old
  • pregnancy of breast feeding

Treatment and study plan

Bachmann's area pacing

Device

In this study, the atrial lead will be targeted to the Bachmann's bundle area, rather than the conventional right atrial appendage pacing site.

Primary outcomes

  1. Success of Bachmann's area pacing

    Time frame: 10 minutes

    Successful Bachmann's bundle area pacing is defined by a reduction of the paced P-wave duration by at least 30 ms when the spontaneous P-wave duration exceeds 120 ms, or by a reduction of the paced P-wave duration by at least 10 ms when the spontaneous P-wave duration is ≤120 ms.

Secondary outcomes

  1. Success of Bachmann's area pacing after 3 months follow-up

    Time frame: 3 months

  2. Success of Bachmann's area pacing after12 months follow-up

    Time frame: 12 months

  3. AF burden after 12 months follow-up

    Time frame: 12 months follow-up

Study contacts

Contact information is provided by the study sponsor or research team.

Jonaz FONT, MD, MSc

CONTACT

[email protected]

00332315118

Sponsors and collaborators

Lead sponsor

University Hospital, Caen

Other

Registry information

Official study title

BACHSTIM REGISTRY: a Feasability Prospective Study of Bachmann's Area Pacing

Important dates

Study start
2026
Primary completion
2027
Study completion
2028
First posted
Mar 12, 2026
Registry last updated
Mar 12, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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