University of Chicago Hospital
Chicago, Illinois, 60637, United States
Location status: Recruiting
Location contact
Adam DuVall, MD
PRINCIPAL_INVESTIGATOR
Recruiting
NCT Number: NCT06868121
AYA OMGYES Sexual Health Study
The purpose of this study is to assess the impact of the web-based intervention OMGYES.com on sexual dysfunction in young adult (YA) female-bodied cancer survivors. This pilot trial seeks to evaluate the intervention's:
* feasibility * acceptability * appropriateness.
Researchers will utilize an active observation period to compare outcomes between those receiving the intervention immediately and those who haven't
Participants will:
* Complete online modules at home * Visit the clinic every 5 weeks for questionnaires
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
18 year–45 year
Sex eligibility
Female
Study type
Interventional
Phase
Not applicable
Primary location
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Age 18 to 45 years
- Diagnosis of cancer between the ages of 15 and 45
- Female genitalia, regardless of gender
- Diagnosed with sexual dysfunction
- Complete Remission and at least two months from a major treatment
- Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial
- Ability to participate in study modules and to respond to surveys
- Ability to understand and the willingness to sign a written informed consent document
Exclusion criteria
- Patients receiving other investigational agents
- Patients expected to be neutropenic or have a significantly high infection risk that would exclude them from vaginal penetration
- Patients who are unable complete the study intervention or surveys
Treatment and study plan
OMGYES.com
OtherOMGYES.com is an interactive website that offers information, video tutorials, interviews, tips, and resources to explore female sexual pleasure through groundbreaking research that's told through the real-life experiences of women of all ages and life stages.
Primary outcomes
-
Feasibility of OMGYES.com using the Feasibility of Intervention Measure (FIM)
Time frame: End of Study (Week 6)
The Feasibility of Intervention Measure (FIM) is a validated questionnaire that utilizes a 5-point Likert scale to evaluate the extent at which an intervention can be successfully used in a clinical setting.
Secondary outcomes
-
Acceptability of OMGYES.com using the Acceptability of Intervention Measure (AIM)
Time frame: End of Study (Week 6)
The Acceptability of Intervention Measure (AIM) is a validated questionnaire that utilizes a 5-point Likert scale to evaluate the extent to which participants deem an intervention agreeable, palatable, or satisfactory.
-
Appropriateness of OMGYES.com using the Appropriateness of Intervention Measure
Time frame: End of Study (Week 6)
The Acceptability of Intervention Measure (AIM) is a validated questionnaire that utilizes a 5-point Likert scale to evaluate the perceived fit, relevance, or compatibility of an intervention for a given population; and/or perceived fit of the intervention to address a particular issue or problem
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
University of Chicago
Other
Registry information
Official study title
Assessing the Impact of a Web-based Educational Program on the Sexual Health Outcomes of Young Adult Female Cancer Survivors ~ A Pilot Trial
Important dates
- Study start
- 2025
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Mar 10, 2025
- Registry last updated
- Jun 5, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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