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OpenTrials
Completed

NCT Number: NCT04683510

Awareness Enhancing Interventions

The purpose of this study is to determine if increasing awareness and, thus, enhancing positive attitudes about research, prior to recruitment attempts, will increase participation in cancer clinical research among African American (AA) cancer survivors so that recruitment efforts can focus on the most optimal and cost- effective approaches

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Key information

Conditions

Age range

50 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Alabama at Birmingham, Birmingham, Alabama, United States

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About this study

In this project, 2000 AA potential AMPLIFI project participants will be randomized to the awareness-enhancing intervention (AWEI) or to the comparison condition in which they do not receive AWEI intervention but only the Adapting Multiple Behavior Interventions that Effectively Improve Cancer Survivor Health (AMPLIFI) basic recruitment strategy (No AWEI). Randomization for the AWEI Randomized Controlled Trial (RCT) will occur soon after the AMPLIFI recruitment letter is sent, and AWEI interventions will be delivered over a two-week period between the AMPLIFI recruitment invitation letter and the AMPLIFI recruitment call. Survivors randomized to AWEI intervention will be exposed to 8 different combinations of the AWEI components according to different types of strategies and type of information reflecting the survivor voice or not. Subsequent to the AMPLIFI recruitment call, a 20% random sample of cancer survivors will be surveyed over the phone to assess intervention fidelity.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • African American/Black
  • adults (age ≥50 years old)
  • diagnosed with obesity/physical activity associated cancers that have a 70% or greater 5-year relative cancer-free survival rate multiple myeloma, localized kidney cancer and loco- regional cancers of the colorectum, female breast, prostate, endometrium, and ovary).
  • 1-5 years post diagnosis
  • reside in an area with wireless coverage
  • In the AMPLIFI recruitment pool

Treatment and study plan

Navigation - Study Specific - Researcher Voice

Other

The intervention is delivered over the telephone

Navigation - Study Specific - Cancer Survivor Voice

Other

The intervention is delivered over the telephone

Navigation - Research General - Researcher Voice

Other

The intervention is delivered over the telephone

Navigation - Research General - Cancer Survivor Voice

Other

The intervention is delivered over the telephone

Brochure - Study Specific - Researcher Voice

Other

The invention is mailed to the participant in a brochure.

Brochure - Study Specific - Cancer Survivor Voice

Other

The invention is mailed to the participant in a brochure.

Brochure - Research General - Researcher Voice

Other

The invention is mailed to the participant in a brochure.

Brochure - Research General - Cancer Survivor Voice

Other

The invention is mailed to the participant in a brochure.

Primary outcomes

  1. Recruitment Yield

    Time frame: within 3 months of receiving intervention

    measured by the proportion of targeted survivors who, at the time of the recruitment call, after the screening process is complete, decide to participate in AMPLIFI.

Sponsors and collaborators

Lead sponsor

University of Tennessee

Other

Collaborators

  • National Cancer Institute (NCI)
  • University of Alabama at Birmingham

Registry information

Official study title

Increasing Recruitment of Underrepresented Cancer Survivors With Awareness Enhancing Interventions

Acronym: AWEI

Important dates

Study start
2021
Primary completion
2024
Study completion
2025
First posted
Dec 24, 2020
Registry last updated
May 4, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.