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Completed

NCT Number: NCT01723267

Automated 3D (SonoAVC) Versus 2D Ovarian Follicles Assessment in IVF Cycles: a Randomized Controlled Trial

Accurate assessment of the size of follicles is important in IVF treatment.Timing of oocyte maturation and subsequent egg collection is largely based on follicle size. An accurate assessment of follicle size and appropriate timing of HCG result in retrieval of more mature oocytes, improved fertilization and higher pregnancy rates. in 3D technology- fter the capturing of a 3D image of an ovary, SonoAVC automatically analyzes the volume dataset, identifies the boundaries of hypoechoic follicles, and provides estimates of their absolute dimensions. These measurements include the largest diameters in three orthogonal planes, the mean follicular diameter (MFD), the volume of the follicle, and the volume-based diameter (d(V)) of the follicle. In the current study the investigators aim to evaluate the use of this automated technique of follicle measurement vs. standard 2D technology on the timing of oocyte maturation and subsequent oocyte retrieval. The investigators speculate that 3D assessment will increase the rate of mature oocyte collection, and eventually will improve other treatment outcomes such as fertilization rate.

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Key information

Age range

18 year–39 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

IVF Unit, Rabin Medical Center

Petah Tikva, 49100, Israel

About this study

Not desired

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age:18-39, cycle number 1-4

Exclusion criteria

  • PCOS
  • Endometriosis
  • Poor ovarian response
  • TESA sperm

Treatment and study plan

3D follicles assessment

Other

3D ultrasound evaluation in IVF treatment (vs 2D ultrasound)

2D follicles assessment

Other

2D ultrasound in IVF treatment (vs 3D ultrasound)

Primary outcomes

  1. percentage of matured oocytes

    Time frame: one IVF cycle (within two weeks)

Secondary outcomes

  1. Fertilization rate in ICSI

    Time frame: one IVF cycle/ patient (within two weeks)

Sponsors and collaborators

Lead sponsor

Rabin Medical Center

Other

Registry information

Official study title

Automated 3D (SonoAVC) vs 2D Ovarian Follicles Assessment in IVF Cycles: a Randomized Controlled Trial

Important dates

Study start
2012
Primary completion
2013
Study completion
2013
First posted
Nov 7, 2012
Registry last updated
Apr 12, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.