Autologous Serum Skin Test and Serum IL-18 Levels in Chronic Idiopathic Urticaria and Respiratory Allergic Diseases

One of the proposed mechanisms in CU is autoimmunity. It was shown by a positive response to autologous serum skin test (ASST)in almost half of chronic urticaria (CU) patients. IL-18 also play a role in autoimmune disorders. The investigators aim was to investigate the relationship of ASST and IL-18 in CU and respiratory allergic diseases.

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Key information

Conditions

Urticaria Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Respiratory Allergic Diseases Skin Diseases Skin Diseases, Vascular Skin and Connective Tissue Diseases

Age range

16 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Eskisehir Osmangazi University

Eskişehir, 26040, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

adult patients
chronic urticaria patients
stable asthma patients
allergic rhinitis patients with sensitized to pollens
normal controls without atopic and skin disease.

Exclusion criteria

unwillingness to the study
other dermatological problems that could affect the skin test
use of antihistamine drugs

Treatment and study plan

autologous serum skin test, serum IL-18

Procedure

Sponsors and collaborators

Lead sponsor

Eskisehir Osmangazi University

Other

Registry information

Important dates

Study start: 2009
First posted: Mar 24, 2010
Registry last updated: Mar 24, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed