Autobiographical Memory Organization in Schizophrenia

The aim of the study is to investigate the temporal organization of autobiographical memory in patients with schizophrenia. Patients and control participants will be invited separately to participate in a 1hour walk in the city of Strasbourg and at the same time, to carry an automatic camera around their neck, which is called SenseCam®. Pictures obtained with SenseCam® will be later presented to the participants during the session of test. They will be asked to determine the chronological order of 12 pictures corresponding to 12 particular events of the tour. Then they will be asked to watch the complete sequence of photos from the tour and to determine the beginning and ending of the events that have occurred during the tour. According to the investigators hypotheses, patients should have difficulty to find out the correct chronological order of the photos and to determine the appropriate beginnings and endings of the events

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Key information

Conditions

Schizophrenia Mental Disorders Schizophrenia Spectrum and Other Psychotic Disorders

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Service de psychiatrie 1 , Les Hôpitaux Universitaires de Strasbourg

Strasbourg, Alsace, 67091, France

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

for both patients and controls
male or female willing to participate and who have signed up the legal document
under the protection of health insurance for patients only
schizophrenia or schizo-affective disorder according to the DSM-IV-TR criteria
clinically stable for at least 2 months for controls only
no psychiatric history

Exclusion criteria

for both patients and controls
current severe or unstable somatic illness
neurological history (epilepsia, brain injury, brain surgery…)
current substance use disorder (DSM-IV-TR)
current major depressive disorder (DSM-IV-TR)
mental retardation (IQ < 70)
pregnancy, breast feeding
current legal control for patients only
treatment comprising benzodiazepines
benzodiazepines intake during the last 3 weeks for controls only
psychotropic intake during the last 3 weeks

Treatment and study plan

questionary

Other

Primary outcomes

Specificity of memories recovered by using the SenseCam camera during the trial

Time frame: 1 month

SenseCam®(corresponding to the name of the automatic camera that participants will be asked to carry around their neck during the city-tour)

Sponsors and collaborators

Lead sponsor

University Hospital, Strasbourg, France

Other

Registry information

Acronym: AMOrSchiz

Important dates

Study start: 2014
Primary completion: 2017
Study completion: 2017
First posted: Oct 7, 2015
Registry last updated: Dec 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed