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Completed

NCT Number: NCT04584138

Autobiographical Memory

This study aims at the assessment of eye movement during autobiographical retrieval (i.e., retrieval of personal memories) in patients with Alzheimer's Disease.

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Key information

Conditions

Alzheimer's Disease Alzheimer Disease Autobiographical Memory Brain Diseases Central Nervous System Diseases Dementia Eye Movement Memory Mental Disorders Nervous System Diseases Neurocognitive Disorders Neurodegenerative Diseases Tauopathies

Age range

18 year–100 year

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU de Nantes

Nantes, 44000, France

About this study

There is an increased interest in the study of eye movements during the retrieval of autobiographical memories and recent research has demonstrated how retrieval of autobiographical memory can activate eye movement. This research has been however mainly concerned with young adults and, until now, little is known about the relationship between eye movement and autobiographical memory in patients with Alzheimer's Disease. The aim of the current study is therefore to evaluate eye movements during the retrieval of autobiographical memories in patients with Alzheimer's Disease.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of Alzheimer's Disease at the mild stage

Exclusion criteria

  • Neurological/psychiatric disorders (other than Alzheimer's Disease)

Treatment and study plan

Study of eye movements

Behavioral

The assessment of eye movement during autobiographical retrieval (i.e., retrieval of personal memories) in patients with Alzheimer's Disease.

Primary outcomes

  1. Number of fixations and saccades

    Time frame: Four weeks (from assessment till analysis)

    Number

  2. Duration of fixations and saccades

    Time frame: Four weeks (from assessment till analysis)

    Duration in milliseconds

Secondary outcomes

  1. Pupil size

    Time frame: Four weeks (from assessment till analysis)

    In millimeter

Sponsors and collaborators

Lead sponsor

Nantes University Hospital

Other

Registry information

Official study title

Eye Movement During Autobiographical Memory in Alzheimer's Disease

Acronym: EMAM

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Oct 12, 2020
Registry last updated
Mar 23, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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