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OpenTrials
Recruiting

NCT Number: NCT06553300

Auto Transplantation of Wisdom Teeth

Autotransplantation emerges as a viable alternative to tooth extraction and prosthetic restoration when conventional endodontic treatments are unfeasible or contraindicated. The success of autotransplantation is influenced by diverse factors, including root development stage, tooth morphology, surgical technique, extraoral duration, recipient socket shape, recipient bed vascularity, and periodontal ligament cell vitality. Preserving periodontal ligament quality and achieving tissue adaptation are pivotal for successful tooth transplantation. Successful donor tooth replacement is influenced by variables like fitting attempts, alveolus-root distance, extra-alveolar time, surgical skill, and extraction trauma intensity.

Recruiting

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Key information

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Cleveland Dental Institute

Cleveland, Ohio, 44128, United States

Location status: Recruiting

Location contact

Ahmed Hashem, DDS

PRINCIPAL_INVESTIGATOR

Luis M De la Rosa, DDS

PRINCIPAL_INVESTIGATOR

Mustafa Khallaf, DDS

PRINCIPAL_INVESTIGATOR

Nelza Baladi, DDS

PRINCIPAL_INVESTIGATOR

Waleed Elmallah, DDS

CONTACT

216-727-0234

Waleed Elmallah, DDS

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • male and female
  • aged between 20 and 50 years
  • devoid of systemic ailments
  • complying with the study procedures
  • holding an Anesthesiologists classification of 1 or 2
  • possessing mandibular or maxillary immature wisdom teeth

Exclusion criteria

  • systemic diseases that might impede the healing process
  • Patients with pacemakers
  • Individuals harboring allergies to medications or antibiotics
  • active smokers
  • patients afflicted with periodontal diseases

Treatment and study plan

Autotransplantation with PRF

Procedure

Autotransplantation of Wisdom teeth to the extracted socket of removed broken down posterior teeth with the application of PRF

Autotransplatation Only

Procedure

Autotransplantation of Wisdom teeth to the extracted socket of removed broken down posterior teeth.

Primary outcomes

  1. Radiographic success

    Time frame: one year

    The success of auto-transplanted immature third molars with and without Platelet-Rich Fibrin will be assessed over a year period.

Study contacts

Contact information is provided by the study sponsor or research team.

Luis M De la Rosa, DDS

CONTACT

[email protected]

917-861-5881

Nelza Baladi, DDS

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

Cleveland Dental Institute

Other

Registry information

Official study title

Auto Transplantation of Wisdom Teeth With or Without Platelet Rich Fibrin for Replacement of Non-Restorable Posterior Teeth.

Important dates

Study start
2024
Primary completion
2024
Study completion
2025
First posted
Aug 14, 2024
Registry last updated
Aug 14, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.