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Completed

NCT Number: NCT07027215

Augmented Sensory in Cancer-Related Neuropathic Patients"

this research studied the effect of augmented sensory feedback program on motor control and risk of falling in patient with CIPN.

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Key information

Conditions

Age range

35 year–60 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Physical Therapy South Valley University

Luxor, Qena Governorate, Egypt

About this study

Design: A randomized control trial was conducted to investigate the impact of augmented sensory feedback paradigm on motor control and risk of falling in patient with Chemotherapy-induced peripheral neuropathy. Data were collected pre and post treatment from out-patient clinic of the Faculty of Medicine and Faculty of Physical Therapy South Valley University, between January 2023and March 2024. The study was approved by the ethical committee of the Faculty of Physical Therapy, South Vally University, Egypt. The study protocol was explained in detail to every patient and signed written consent was obtained before participation.

Participants: forty female patients with CIPN were recruited from out-patient clinic of the Faculty of Medicine and Faculty of Physical Therapy South Valley University, between January 2023and March 2024.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Forty female with age from 35-60 years
  • clinically diagnosed with CIPN after recovery from stage I or II breast cancer
  • The strength at the toes, ankles, knees, and hips, as determined by manual muscle tests, of at least 3/5.
  • The patients can walk independently with or without any assistive devices.

Exclusion criteria

  • Patients with a history of hereditary peripheral neuropathy
  • Diseases that may contribute to peripheral nerve damage, such as diabetes or renal insufficiency, alcohol abuse, HIV, and vasculitis.
  • Patient who had central or peripheral neurologic disease, brain or spinal cord metastases
  • Orthopedic problems influencing gait, or foot ulcer at the moment of intake.
  • Patients with vestibular or neurological problems influencing gait parameters
  • Subjects who had participated in regular exercise, as defined as 150 min of light-to-moderate intensity exercise per week over the past year, were excluded from this trial.

Treatment and study plan

Gradual Intermittent pneumatic compression therapy (IPC),Balance excercises.PNF technique

Combination Product

PNF technique

Other names: Balance Exercises

selected physical therapy program as arm excercises

Combination Product

selected physical therapy program only. The program consisted of (core exercises, AROM exercises, and stretching exercises for LL for 18 sessions every other day, over 6 weeks

Primary outcomes

  1. improvement of balance which was assessed by fall risk scale

    Time frame: one and half month

    improvement in feet sensitivity and motor control and risk of falling in both groups in favor of the study group.

  2. Stability measures

    Time frame: one and half month

    postural stability was measured using a Biodex Balance System SD (950-440 with version 4.X software)

  3. Sensory feedback

    Time frame: one and half month

    Sensory feedback was assessed by using Semmes-Weinstein monofilament (SWM)

Sponsors and collaborators

Lead sponsor

Isra University, Jordan

Other

Registry information

Official study title

Impact of Augmented Sensory Feedback on Motor Control and Risk of Falling in Cancer-Related Neuropathic Patients"

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Jun 18, 2025
Registry last updated
Dec 22, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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