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NCT Number: NCT06552195

Augmented Reality in Learning Anatomy: The TEACHANATOMY Randomized Cross-over Trial

Cadaver use in anatomy education is undergoing several limitations in many universities, due to high costs, time constraints and supply difficulties. As alternatives to cadaver dissections, new teaching methods based on visual technologies, such as augmented reality (AR), are being implemented worldwide.

Augmented reality (AR), based on virtual interactive 3-dimensional elements (holograms) overlaid in the real-world, represents a promising alternative to explore the human body. In this study, we will test the efficacy of AR as an alternative teaching method in anatomy education by comparing traditional learning methods based on 2-dimensional (2D) images, videos, and online learning programs with the novel AR learning module The primary endpoint will consist of the score in the final theoretical and practical knowledge tests, assessed at two timepoints: immediately after the study session and after 3 months.

Secondary endpoints will include adverse health symptoms and user experience, assessed immediately after the study session.

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Key information

Age range

18 year–25 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Cadaver use in anatomy education is undergoing several limitations in many universities, due to high costs, time constraints and supply difficulties. As alternatives to cadaver dissections, new teaching methods based on visual technologies, such as augmented reality (AR), are being implemented worldwide.

Augmented reality (AR), based on virtual interactive 3-dimensional elements (holograms) overlaid in the real-world, represents a promising alternative to explore the human body. In this study, we will test the efficacy of AR as an alternative teaching method in anatomy education. Our hypothesis is that learning with AR is more efficient than traditional learning methods.

Preparation: We will prepare 2 fresh-frozen cadaveric specimens to allow visualization of anatomical structure of the shoulder and hips. The cadavers will be obtained from a human body donated for university teaching activities. Using a digital single-lens reflex camera, we will acquire several images. These images will be then converted into a 3D model by the ROCS team at Balgrist University Hospital and optimized for use with the Magic Leap AR headset.

Procedure: Participants (approx. 300) will be randomly assigned to the AR or the traditional learning (TL) group. Each participant will learn one anatomy module with traditional learning methods, which will include books, access to websites, 3D videos, and online learning programs, and one module with the AR-based learning program. The two modules will be administered approximately 3 weeks apart.

Group A: Shoulder anatomy with traditional learning methods and hips anatomy with AR based 3D program.

Group B: Shoulder anatomy with AR based 3D program and hips anatomy with traditional learning methods.

The primary endpoint will consist of the score in the final theoretical and practical anatomy tests, assessed at two timepoints: immediately after the study session and after 3 months.

Secondary endpoints include adverse health symptoms, assessed with a Likert scale survey, and user experience, evaluated using an adapted NASA Task Load Index scale plus additional questions.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Medical students attending the 1st or 2nd year of undergraduate medical education
  • Must not have prior anatomical education

Exclusion criteria

  • Epilepsy
  • Binocular vision disorder such as strabismus
  • Current head and/or neck injuries
  • Inflammation of the scalp and/or eye
  • Amputations or partial amputations of the hands

Treatment and study plan

learning with augmented reality

Other

Study presentation: participants will be given a 10-minute general introduction on the study followed by a 20 minutes tutorial to introduce the HoloLens 2 and the TEACHANATOMY learning platform.

  • Study session: The study session consists of three learning blocks of approximately 20 minutes each, plus a repetition block to assess the acquired knowledge. During the study session participants will be given no time constraints and free breaks.
  • Assessment test: Participants will be assessed with a 30 minutes knowledge assessment test at the end of the study and after three months.
  • Final questionnaire: At the end of the study session participants will be given a questionnaire to assess adverse health symptoms and user experience.

learning with traditional methods

Other
  • Study presentation: participants will be given a 10-minute general introduction on the study followed by a presentation to introduce the study session.
  • Study session: The study session consists of the learning resources most used by students: specific sections from four different neuroanatomy books, access to two websites, two 3D videos, and two online learning programs. During the study session participants will be given no time constraints and free breaks.
  • Assessment test: Participants will be assessed with a 30 minutes knowledge assessment test at the end of the study and after three months.
  • Final questionnaire: At the end of the study session participants will be given a questionnaire to assess adverse health symptoms and user experience

Primary outcomes

  1. knowledge test

    Time frame: immediately after the study session, day 1, and after three months

    The primary outcome will consist of the score in the final theoretical and practical tests. The theoretical test consists of single and multiple-choice questions in which participants will be required to recognize and name the different anatomical structures of the hips or shoulder and their function. In the practical part, participants will be required to mark specific anatomical structures in a 3D-printed anatomical skull model. The duration of the test will be of approximately 30 minutes.

Secondary outcomes

  1. adverse health symptoms

    Time frame: Immediately after the knowledge test, Day 1

    Secondary outcomes will include adverse health symptoms, evaluated with a questionnaire to assess presence and severity of general symptoms (General discomfort, Fatigue, Headache, Dizziness, Nausea, Concentration problems, Disorientation, Neck stiffness/neck pain, No symptoms) and eye-related symptoms (Blurred vision, Difficulty focusing, Double-vision, Dry eyes No symptoms). Presence and severity of symptoms will be rated on a Likert scale from 1 (almost imperceptible) to 10 (extreme).

  2. User experience

    Time frame: Immediately after the Adverse health symptoms, Day 1

    User experience will be assessed using an adapted NASA Task Load Index (5 questions, range, 1-10, with lower scores indicating lower cognitive workload) plus additional 10-point Likert scale and open-ended questions in which participants will be asked to rank their comfort with the material and hardware and the teaching effectiveness of the software or of the traditional learning methods to learn anatomy

Study contacts

Contact information is provided by the study sponsor or research team.

Lukas Zingg, MD

CONTACT

[email protected]

0796644805 ext. +41

Philipp Fürnstahl, Prof.

CONTACT

[email protected]

044 510 73 60 ext. +41

Sponsors and collaborators

Lead sponsor

Balgrist University Hospital

Other

Collaborators

  • ETH Zurich

Registry information

Official study title

Hologram-Based Augmented Reality in Learning Anatomy: The TEACHANATOMY Randomized Cross-over Trial

Important dates

Study start
2024
Primary completion
2024
Study completion
2025
First posted
Aug 13, 2024
Registry last updated
Aug 13, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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