Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
NCT Number: NCT06713668
The goal of this clinical trial is to learn if backup pacing at an increased rate improves hemodynamics in adults with relative bradycardia, a permanent pacemaker, and cardiogenic shock. The main question it aims to answer is:
Does increasing the backup pacing rate to 100 beats per minute lead to improved cardiac index compared to a backup pacing rate of 75 beats per minute
Participants who are already hospitalized in the Cardiovascular Intensive Care Unit with a permanent pacemaker and pulmonary artery catheter in place will be enrolled in this study. Participants will be exposed to each pacemaker rate in a randomized order with hemodynamics assessed after 10 minutes at each rate.
This study is active but is not currently recruiting participants.
Notify Me18 year and older
All sexes
Interventional
Not applicable
Nashville, Tennessee, 37232, United States
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Patients will have backup pacing programmed to A (75 bpm) and B (100 bpm), randomizing to sequence of exposure A-B or B-A
Time frame: At baseline and 10 minutes after each rate programmed (i.e at 0, 15, and 30 minutes)
Cardiac Index measured by thermodilution (in liters per minute per meters squared)
Time frame: 0, 15, 30 minutes.
Time frame: 0, 15, 30 minutes.
Time frame: 0 ,15, 30 minutes
Time frame: 0, 15, 30 minutes
Time frame: 0, 15, 30 minutes
Time frame: 0, 15, 30 minutes
Time frame: 0, 15, 30 minutes
Time frame: 0, 15, 30 minutes
Time frame: 0, 15, 30 minutes
Time frame: 0, 15, 30 minutes
Time frame: 0, 15, 30 minutes
Time frame: 0, 15, 30 minutes
Time frame: 0, 15, 30 minutes
Time frame: 0, 15, 30 minutes
Time frame: 0, 15, 30 minutes
Time frame: 0, 15, 30 minutes
Time frame: 0, 15, 30 minutes
Time frame: 0, 15, 30 minutes
Vanderbilt University Medical Center
Other
Augmented Pacing for Shock in the Cardiac Intensive Care Unit - A Pilot Patient-level Crossover Trial
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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