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OpenTrials
Completed

NCT Number: NCT03204006

Attenuation of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation With Single Dose of Dexmedetomidine in Hypertensive Patients.

Attenuation of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation With Single Dose of Dexmedetomidine in Hypertensive Patients.

Completed

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Key information

Conditions

Stress Response During Laryngoscopy Intubation

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Assiut University Hospital

Asyut, 71515, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • - Age group 20-60 years
  • ASA grade 1 and 2
  • control hypertensive patients.

Exclusion criteria

  • - Consent not given
  • ASA Grade 3 and 4
  • history of myocardial ischemia or infarction, or had an abnormal ECG on admission to the hospital
  • Patients with cardiovascular, pulmonary, hepatic, and renal disease.
  • Patients on B blockers.
  • patients with difficult airway; laryngoscopy and intubation time more than 20 s, or requiring more than two attempts will be exclude from the study.

Treatment and study plan

Dexmedetomidine

Drug

Dexmedetomidine preinduction

Sterile Saline

Drug

normal saline preinduction

Primary outcomes

  1. heart rate

    Time frame: through first 15 min post-induction of anesthesia

Secondary outcomes

  1. systolic blood pressure

    Time frame: through first 15 min post-induction of anesthesia

  2. diastolic blood pressure

    Time frame: through first 15 min post-induction of anesthesia

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Attenuation of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation With Single Dose of Dexmedetomidine in Hypertensive Patients

Important dates

Study start
2018
Primary completion
2020
Study completion
2020
First posted
Jun 29, 2017
Registry last updated
Apr 7, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.