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OpenTrials
Completed

NCT Number: NCT02014194

Attentional Bias Modification Treatment in OCD

Obsessive-compulsive disorder is a chronic condition. Even with proper treatment, no significant improvement is reached in about 30% to 40% of patients. Thus, the development of new treatment strategies is necessary. The attentional bias - ability to aversive stimuli in capturing the attention of an individual compared to a neutral stimulus - has been extensively studied. Already training attentional bias modification has been shown effective in reducing anxiety present in other anxiety disorders.This project aims to: 1 - generate knowledge on attentional bias in individuals with OCD through the use of a standardized protocol developed for OCD; 2 - available to the scientific community the first specific paradigm for the study of attentional bias in OCD patients, 3 - test the effectiveness of a training protocol for reversing attentional bias in individuals with OCD.

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Key information

Conditions

Obsessive-Compulsive Disorder Anxiety Disorders Mental Disorders

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Sao Paulo Medical School

São Paulo, 05403010, Brazil

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

- 30 patients with obsessive-compulsive diagnosis according to DSM-V (with cleaning and or symmetry dimensions)

  • 30 health controls

Exclusion criteria

- doing any kind of behavioral therapy in the moment

Treatment and study plan

attentional bias modification treatment

Behavioral

The attentional bias modification treatment is a behavioral computerized program (software e-prime)

Primary outcomes

  1. Percentage of reduction of attentional bias

    Time frame: Patients will be followed an expected average of 7 weeks (baseline, 2 sessions per week - totalizing 5 weeks, 10 sessions and a session after end of treatment). Measures of attentional bias will be assessed in baseline, session 5 and after session 10.

Secondary outcomes

  1. Reduction of anxiety symptoms

    Time frame: Baseline, session 5 and end of treatment (after session 10) (expected average of 7 weeks)

Sponsors and collaborators

Lead sponsor

Roseli Shavitt

Other

Registry information

Official study title

Attentional Bias and Attentional Bias Modification Treatment in Obsessive-compulsive Disorder

Important dates

Study start
2013
Primary completion
2016
Study completion
2016
First posted
Dec 18, 2013
Registry last updated
Jan 25, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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