Atrial Fibrillation Recurrence After Cryoballoon Ablation

The purpose of the study is to evaluate the mechanisms of recurrent atrial fibrillation after cryoballoon ablation using the Arctic Front Ablation System. For those with pulmonary vein reconnection, specific sites of reconnection will be evaluated with left atrial intracardiac echo (ICE) guidance. The Achieve mapping catheter will be evaluated head-to-head with our current method of ICE-guided recordings from a conventional mapping catheter with high output pulmonary venous pacing.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Atrial Fibrillation Arrhythmias, Cardiac Cardiovascular Diseases Heart Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

UPMC Passavant, Pittsburgh, Pennsylvania, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients undergoing re-do catheter ablation procedure after index procedure with cryoballoon ablation
At least 18 years old
Able to read and understand informed consent

Exclusion criteria

Unable to give informed consent

Treatment and study plan

Use of the Achieve catheter followed by ICE-guided mapping catheter

Other

Primary outcomes

Presence or absence of pulmonary vein isolation or reconnection

Time frame: During repeat cryoballoon ablation procedure

Sponsors and collaborators

Lead sponsor

University of Pittsburgh

Other

Collaborators

Medtronic

Registry information

Official study title

Mechanisms and Patterns of Atrial Fibrillation Recurrence After Cryoballoon Ablation

Important dates

Study start: 2013
Primary completion: 2019
Study completion: 2019
First posted: Jan 21, 2013
Registry last updated: Feb 12, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed