Skip to main content
OpenTrials
Completed

NCT Number: NCT01711190

Astigmatism Post-trabeculectomy

The aim of this project:

1. Confirming the modification in corneal astigmatism after trabeculectomy with MMC and intracameral administration of bevacizumab. 2. Medium-term follow up (6 months) of the induced corneal astigmatism. 3. Investigating correlations between postoperative astigmatism, particularly with the postoperative IOP.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Glaucoma Astigmatism Eye Diseases Ocular Hypertension Refractive Errors

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Sint-Raphaël hospital

Leuven, Vlaams-Brabant, 3000, Belgium

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Primary open angle glaucoma
  • Normal tension glaucoma
  • Pseudoexfoliation glaucoma
  • Pigment dispersion glaucoma

Exclusion criteria

  • Patients who refuse to sign the informed consent.
  • Patients with primary angle closure glaucoma (PACG).
  • Patients younger than 18 years old.
  • Other ocular diseases besides glaucoma.
  • Significant corneal opacities.
  • Refractive error more than + or -6.00 diopters.
  • Visual acuity less than 0.05
  • Previous intra-ocular surgery (except cataract surgery more than six months preceding the trabeculectomy).
  • Laser treatment for glaucoma within 6 months of the surgery.

Treatment and study plan

trabeculectomy

Procedure

Filtering surgery to reduce the intra-ocular pressure.

Primary outcomes

  1. Change in ocular cylinder and axis untill 6 months after trabeculectomy.

    Time frame: pre-operative until 6 months post-operative

    Comparing the change in corneal cylinder, axis and IOP before the operation and 1,3 and 6 months after the operation. We will compare these vectors by vector analyses.

Sponsors and collaborators

Lead sponsor

Universitaire Ziekenhuizen KU Leuven

Other

Registry information

Official study title

The Effect of Trabeculectomy on Astigmatism.

Important dates

Study start
2012
Primary completion
2012
Study completion
2012
First posted
Oct 22, 2012
Registry last updated
Dec 20, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.