Associations Between Air Pollutants Exposures and Respiratory System Study

Epidemiological investigations has suggested exposure to air pollution linked with respiratory disease, especially chronic obstructive pulmonary disease. However, the potential mechanisms of adverse effects remains scare. The present study will assess the association between air pollutants and respiratory related parameters to elucidate possible mechanisms.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Chronic Obstructive Pulmonary Disease Chronic Disease Disease Attributes Lung Diseases Lung Diseases, Obstructive Pathologic Processes Pathological Conditions, Signs and Symptoms Pulmonary Disease, Chronic Obstructive Respiratory Tract Diseases

Age range

23 year–82 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Long-term residents, aged >23 and <82 years

Exclusion criteria

Severe cardiopulmonary diseases, active inflammatory diseases, cancer

Treatment and study plan

Primary outcomes

Lung Function indices were performed in peking university third hospital

Time frame: Repeated-measure study was conducted from November,2014 to January,2016,lung function was measured by every four months

Lung Function indices including FEV1(ml), FVC(ml),the ratio of FEV1/FVC et, al.. When we perform data analysis,these parameters will be expressed as the percentage of the predicted values based on the subject-specific sex, age,height and weight.

Secondary outcomes

Inflammation related biomarkers were measured by flow cytometry

Time frame: Repeated-measure study was conducted from November,2014 to January,2016,biomarkers were measured by every four months

Inflammation related factors including IL,TNFa et, al. all biomarkers units are pg/ml.

Sponsors and collaborators

Lead sponsor

Peking University Third Hospital

Other

Collaborators

Peking University

Registry information

Important dates

Study start: 2014
Primary completion: 2016
Study completion: 2016
First posted: Nov 15, 2016
Registry last updated: Nov 15, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed