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NCT Number: NCT06218901

Association of Psychological Distress in Patients With Lung Cancer

Psychological distress is a multi-factorial experience of a psychological, social, spiritual, and/or physical nature that may interfere with one's ability to cope effectively with cancer, physical symptoms and treatment. Psychological distress is common and affects the efficacy and prognosis of patients with lung cancer. The systematic anti-tumor therapy may effectively relieve psychological distress including anxiety, depression, and fatigue in patients with advanced lung cancer, the relief of the psychological distress can in turn improve the therapeutic effect.

In summary, this study is to explore the associations of (dynamic) psychological stress with the efficacy and survival of anti-tumor therapy including immunotherapy and targeted therapy for advanced lung cancer patients.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Shanghai Chest Hospital

Shanghai, Shanghai Municipality, 200030, China

Location status: Recruiting

Location contact

Xiaomin Niu

CONTACT

[email protected]

(86) 21 22200000 ext. 3703

Xiaomin Niu

PRINCIPAL_INVESTIGATOR

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Histologically proven diagnosis of lung cancer
  • 18 years of age or older
  • Ability to understand and the willingness to sign a written informed consent document

Exclusion criteria

  • Not willing to participate in this clinical trial

Treatment and study plan

Immunotherapy

Drug

Targeted Therapy Agent

Drug

Primary outcomes

  1. Objective response rate (ORR)

    Time frame: 20 years

    Collect detailed clinical information on patients with SCLC via the electronic medical records

  2. Disease control rate (DCR)

    Time frame: 20 years

    Collect detailed clinical information on patients with SCLC via the electronic medical records

  3. Progression-free survival (PFS)

    Time frame: 20 years

    Collect detailed clinical information on patients with SCLC via the electronic medical records

Secondary outcomes

  1. Overall survival (OS)

    Time frame: 20 years

    Collect detailed clinical information on patients with SCLC via the electronic medical records

Study contacts

Contact information is provided by the study sponsor or research team.

Xiaomin Niu

CONTACT

[email protected]

(86) 21 22200000 ext. 3703

Sponsors and collaborators

Lead sponsor

Shanghai Chest Hospital

Other

Registry information

Official study title

the Association of Psychological Distress in Patients With Advanced Lung Cancer Treated With Immunotherapy or Targeted Therapy

Acronym: Life-Score

Important dates

Study start
2016
Primary completion
2027
Study completion
2028
First posted
Jan 23, 2024
Registry last updated
May 22, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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