Skip to main content
OpenTrials
Completed

NCT Number: NCT05369702

Association of Coronary Artery Disease With Lewis and ABO Blood Group Phenotypes

Primary objective- To study the association of Lewis antigen and A, B, O blood group phenotypes with coronary artery disease patients attending the tertiary care hospital in Kerala.

The secondary objective-To find the association of Lewis antigen and A, B, O blood group phenotypes with smoking, alcohol use, diabetes, hypertension and dyslipidemia.

A case-control study to compare the prevalence of Lewis(a-b-) blood group among confirmed cardiac cases with the prevalence of the same among the general population and thereby find out if individuals with Lewis(a-b-) are more at risk of developing coronary artery disease. This may provide an economical and simple method for identifying subjects at increased risk for coronary artery disease and subsequently lead to more focused preventive measures and eventually to a specific treatment.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Coronary Artery Disease Arterial Occlusive Diseases Arteriosclerosis Cardiovascular Diseases Coronary Disease Heart Diseases Myocardial Ischemia Vascular Diseases

Age range

30 year–55 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Jubilee Mission Medical College & Research Institute

Thrissur, Kerala, 680005, India

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients in the age group of 30-55 years at the time of data collection diagnosed with coronary artery disease based on positive changes in coronary angiogram (more than 70% coronary stenosis)

Exclusion criteria

  • Patients with other systemic illnesses like malignancy, autoimmune diseases.
  • Patients who were not willing to participate in the study.

Treatment and study plan

Primary outcomes

  1. Prevalence of Lewis and ABO blood group phenotypes in cases and controls.

    Time frame: Lewis and ABO phenotype of the study participants was determined immediately after sample collection

    Prevalence Lewis and ABO phenotype in cases will be compared to prevalence of the same in controls.

Sponsors and collaborators

Lead sponsor

Jubilee Mission Medical College and Research Institute

Other

Registry information

Official study title

Association of Coronary Artery Disease With Lewis and ABO Blood Group Phenotypes- A Case Control Study

Important dates

Study start
2019
Primary completion
2021
Study completion
2021
First posted
May 11, 2022
Registry last updated
May 16, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.