Skip to main content
OpenTrials
Completed

NCT Number: NCT03484260

Association Between the Prevalence of Cardiovascular Risk Factors and New Use of Testosterone

We will investigate if testosterone is preferentially given to patients at higher risk of cardiovascular events. If this is the case, then observational studies may be prone to selection bias resulting in overestimation of the cardiovascular risk associated with testosterone when compared to a healthier population not taking testosterone

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Hypogonadism Endocrine System Diseases Gonadal Disorders

Age range

18 year and older

Sex eligibility

Male

Study type

Observational

Primary location

Many Locations

Berlin, 13342, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All male individuals in the source population with a first testosterone use during the study period will be included as cases. The date of the GP consultation associated with the first testosterone prescription will be designated as the index day.

Exclusion criteria

  • Patients of less than 18 years on the index day, with less than 2-year contribution to the CPRD-HES link before the index day, or with use of testosterone before the study period will be excluded from the group of cases.

Treatment and study plan

Testosterone Product

Drug

Men used testosterone product following prescription

Primary outcomes

  1. Estimation of the association between cardiovascular risk factors and initiation of testosterone therapy

    Time frame: Retrospectively from 01 January 2001 to 31 March 2016

Sponsors and collaborators

Lead sponsor

Bayer

Industry

Registry information

Important dates

Study start
2018
Primary completion
2018
Study completion
2018
First posted
Mar 30, 2018
Registry last updated
May 14, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.