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OpenTrials
Completed

NCT Number: NCT06473324

Association Between Preoperative Hyperglycemia and Postoperative Delirium in Geriatric Hip Fracture Patients

This retrospective study aims to collect electronic medical record data from Dandong central hospital spanning from January 2013 to November 2023. The collected data does not contain any personally identifiable information or breach privacy. Additionally, this study design does not involve active intervention measures or patient recruitment. The research aims to investigate the correlation between preoperative blood glucose levels in elderly hip fracture patients and postoperative delirium.

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Key information

About this study

A retrospective observational study is planned to explore specific phenomena or associations using electronic medical record data. The collected data does not contain any personally identifiable information or compromise privacy. Additionally, this study design does not involve active intervention measures or patient recruitment. The study data is sourced from the electronic medical record system of hospitalized patients and has received approval from the hospital's research center, with ongoing supervision by the hospital's ethics committee. The study aims to investigate the correlation between preoperative blood glucose levels in hip fracture patients and postoperative complications.

The retrospective study aims to collect electronic medical record data spanning from January 2013 to November 2023. The data collection process is consistently monitored and verified by the hospital's ethics committee. Throughout the study, adherence to the ethical principles outlined in the 1964 Helsinki Declaration is ensured, and institutional review board (IRB) approval has been obtained for all aspects of the research.

The study aims to provide valuable evidence-based medicine for clinical practitioners by examining the relationship between preoperative persistent hyperglycemia in elderly hip fracture patients and postoperative delirium. Furthermore, it seeks to offer clinical insights for early identification and intervention management of high-risk postoperative delirium patients (POD).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who have undergone surgical treatment for hip fractures.

Exclusion criteria

  • Multiple or pathological hip fractures.
  • Emergent surgery.
  • Age below 60 years.
  • Incomplete electronic medical records or preoperative blood glucose levels were assessed fewer than two times.
  • Presence of neurological and psychiatric disorders, except dementia.

Treatment and study plan

Primary outcomes

  1. Number of Participants with Postoperative Delirium

    Time frame: up to 2 months

    Postoperative Delirium (POD) manifests as acute cognitive dysfunction and consciousness disorder, characterized by changes in attention or consciousness that cannot be attributed to pre-existing cognitive impairments. Typical symptoms include hallucinations, delusions, agitated behavior, disordered speech, decreased attention, confusion, unclear consciousness, and disrupted sleep-wake cycles. Moreover, POD typically occurs within the first five days after surgery, particularly within the initial 48 hours, and exhibits significant fluctuations.

Sponsors and collaborators

Lead sponsor

Wenbo Ding

Other

Registry information

Official study title

Association Between Preoperative Persistent Hyperglycemia and Postoperative Delirium in Geriatric Hip Fracture Patients

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Jun 25, 2024
Registry last updated
Jun 25, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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