Association Between Peri-procedural Myocardial Injury and Quantitative Blood Flow Ratio

to apply angiography-based quantitative blood flow ratio to quantify the severity of the stenosed coronary artery prior to percutaneous coronary intervention, and monitor per-procedural myocardial injury based on the troponin level.Finally, to find the relationship between quantitative blood flow ratio results and myocardial injury degree.

Completed

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Key information

Conditions

Coronary Arterial Disease (CAD)

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Observational

Primary location

the First Affiliated Hospital of Xiamen University

Xiamen, Fujian, 361003, China

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

unstable angina patients

Exclusion criteria

(1) multivessel diseases needed to be bypassed; (2) no track of high-sensitivity troponin I (hs-CTNI) level after PCI; (3) the elevated hs-CTNI level before PCI; (4) patients refusal to PCI; (5) side branch occlusion after PCI; (6) PCI failure with the main vessels occlusion; (7) eGRF (estimated glomerular filtration rate) less than 30ml/min/1.73m2; (8) no acquisition of QFR results because of the non-ideal angiographic quality.

Treatment and study plan

Primary outcomes

cardiovascular adverse events

Time frame: three months
Major cardiac adverse events

Time frame: three months follow-up

Sponsors and collaborators

Lead sponsor

The First Affiliated Hospital of Xiamen University

Other

Registry information

Official study title

Association Between Angiography-based Quantitative Blood Flow Ratio and Peri-procedural Myocardial Injury：a Cohort Study

Important dates

Study start: 2019
Primary completion: 2023
Study completion: 2023
First posted: Aug 7, 2025
Registry last updated: Aug 7, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed