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NCT Number: NCT06844721

Association Between μFR And CABG Outcomes

The goal of this observational study is to evaluate the association between Murray law-based quantitative flow reserve and outcomes after coronary artery bypass graft surgery.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Coronary Artery Bypass Graft Surgery (CABG)

Age range

19 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Seoul National University Hospital

Seoul, 03080, South Korea

About this study

The goal of this observational study is to evaluate the association between Murray law-based quantitative flow reserve and outcomes after coronary artery bypass graft surgery. By constructing registry database during 10-year periods, several types of study objectives including 'graft patency' and 'long-term clinical outcomes' will be evaluated.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients who underwent isolated off-pump CABG for 3-vessel disease,
  • patients who underwent preoperative coronary angiography that fits for μFR analysis,

Exclusion criteria

  • Patients who underwent on-pump CABG
  • Patients in whom quality of preoperative coronary angiography did not fit for μFR analysis

Treatment and study plan

Primary outcomes

  1. Graft patency rate

    Time frame: 1 year after surgery

    1 year graft patency rate after surgery

  2. Number of participants with Long-term all-cause mortality

    Time frame: From date of enrollment (operation) until the date of death from any cause, assessed up to 15 years").

    All-cause mortality indicates death from any cause during follow-up

Secondary outcomes

  1. Number of partipiciants with major adverse cardiac events

    Time frame: From date of enrollment (operation) until the date of first documented major events or date of death from any cause, whichever came first, assessed up to 15 years

    MACE includes death, repeat revascularization and non-fatal myocardial infraction

Sponsors and collaborators

Lead sponsor

Seoul National University Hospital

Other

Collaborators

  • Shanghai Jiao Tong University School of Medicine

Registry information

Official study title

Association Between Murray Law-Based Angiography-Derived Fractional Flow Reserve and Outcomes After Coronary Artery Bypass Grafting

Important dates

Study start
2008
Primary completion
2025
Study completion
2026
First posted
Feb 25, 2025
Registry last updated
Feb 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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