Skip to main content
OpenTrials
Completed

NCT Number: NCT07084857

Association Between Isokinetic Lower Extremity Muscle Strength and Bone Mineral Density in Elderly Women With and Without Osteoporosis

bone density and muscle strength appear to be more related to each other. Examining the association between muscle strength and bone health is very important in recognizing risk factors for lower extremity muscle weakness.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Osteoporosis Bone Diseases Bone Diseases, Metabolic Metabolic Diseases Musculoskeletal Diseases Nutritional and Metabolic Diseases

Age range

50 year–70 year

Sex eligibility

Female

Study type

Observational

Primary location

Azza Mohammed

Giza, 12511, Egypt

About this study

Dual Energy X-ray Absorptiometry (DEXA) scan will be used to assess hip bone mineral density (BMD) at femoral head region. Isokinetic PT of hip flexors, extensors, abductors and adductors and knee flexors and extensors will be measured using Biodex System 3 Isokinetic Dynamometer. The measured outcomes will be evaluated at an angular velocity of 60°/sec in a concentric mode of muscle contraction for five successive repetitions. Isokinetic testing will be done at the Isokinetic Laboratory, Faculty of Physical therapy, Cairo University.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The group of OP (n=33) has femoral BMD T-scores below -2.5 diagnosed by DEXA scan according to the WHO [8] classification of BMD in 2003,
  • The control group has normal BMD T-scores more than -1.

Exclusion criteria

  • There was any neurological, musculoskeletal, rheumatologic, respiratory or cardiovascular problem.
  • They were receiving medications that result in bone loss such as corticosteroids,
  • They had vertigo, dizziness, or any vestibular problem,
  • They had hyperthyroidism or hyperparathyroidism. 6- They actively participate in sports activities,
  • They underwent previous surgery (e.g; joint replacement) or history of fractures of the lower extremity.

Treatment and study plan

correlational analysis between BMD and isokinetic lower extremity strength

Other

correlational analysis between BMD and isokinetic lower extremity strength

Primary outcomes

  1. isokinetic strength of hip muscles

    Time frame: one month

    isokinetic hip muscle stregth will be measured using Biodex system 3 Isokinetic Dynamometer

  2. Bone mineral density

    Time frame: one month

    bone mineral density measured by dual energy x ray absorptiometry scan

Secondary outcomes

  1. isokinetic strength of knee muscles

    Time frame: one month

    isokinetic hip muscle stregth will be measured using Biodex system 3 Isokinetic Dynamometer

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Association Between Isokinetic Lower Extremity Muscle Strength and Bone Mineral Density in Elderly Women With and Without Osteoporosis: A Case-Control Study

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jul 25, 2025
Registry last updated
Apr 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.