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NCT Number: NCT06579872

Association Between Cardiopulmonary Function and Plantar Pressure in Patients With Chronic Obstructive Pulmonary Disease

It aims to understand the differences in everyday mobility and activity capabilities among patients with varying disease progression and severity, to serve as reference indicators for evaluating the effectiveness of pulmonary rehabilitation exercise training.

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Key information

Age range

45 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Fu Jen Catholic University Hospital, Fu Jen Catholic University

New Taipei City, 24352, Taiwan

Location status: Recruiting

Location contact

Ke-Yun Chao, PhD

CONTACT

[email protected]

+886-905-301-879

Ke-Yun Chao, PhD

PRINCIPAL_INVESTIGATOR

About this study

Background: Chronic respiratory diseases and Chronic Obstructive Pulmonary Disease (COPD) are major causes of chronic illness and death worldwide. Patients with chronic respiratory diseases experience muscle weakness and respiratory difficulties, leading to restricted physical activity, decreased functional capacity, exercise intolerance, and limb muscle atrophy. While exercise training can effectively improve limb strength, there is a lack of objective data exploring different disease progressions and clinical cardiopulmonary limitations, hence this study utilizes plantar pressure distribution to research lower limb strength and cardiopulmonary function in patients, hoping to identify relevant indicators for necessary exercise training.

Methods: The study plans to enroll 60 participants, divided into two groups (30 in the control group and 30 in the case group) matched 1:1. The study will be conducted at the pulmonary rehabilitation therapy room on the sixth floor of Fu-Jen Catholic University Hospital. In addition to basic demographic and clinical physiological parameters, all participants will undergo the 6-minute walk test, the timed up and go test, simple pulmonary function tests, body composition analysis, and statistical analysis.

Effect: The trial is expected to effectively determine which patients require exercise training based on the correlation between plantar pressure analysis and results from the 6-minute walk test and timed up and go test. These results are anticipated to correlate positively with disease severity.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 45 and 65 years
  • Patients with chronic respiratory diseases requiring pulmonary rehabilitation
  • Signed informed consent form

Exclusion criteria

  • Current tracheostomy
  • Home use of oxygen therapy or ventilators
  • Diagnosed with severe left heart failure (NYHA III-IV)
  • Patients diagnosed with neuromuscular diseases
  • Had an acute exacerbation of COPD in the past three months
  • Unable to perform cardiopulmonary exercise testing

Treatment and study plan

Plantar pressure

Other

foot pressure analysis, cardiopulmonary function, and mobility in patients with chronic respiratory diseases

Primary outcomes

  1. plantar pressure

    Time frame: 20 minutes

    The correlation between foot pressure indices and functional tests

Secondary outcomes

  1. cardiopulmonary function

    Time frame: 20 minutes

    The correlation between foot pressure indices and cardiopulmonary function

  2. self-feedback questionnaires

    Time frame: 20 minutes

    The correlation between foot pressure indices and self-feedback questionnaires

Study contacts

Contact information is provided by the study sponsor or research team.

Ke-Yun Chao, PhD

CONTACT

[email protected]

+886-905-301-879

Sponsors and collaborators

Lead sponsor

Fu Jen Catholic University

Other

Registry information

Official study title

Association Between Cardiopulmonary Function, Mobility, Walking Ability, and Plantar Pressure Changes in Patients With Chronic Obstructive Pulmonary Disease: A Case-Control Study

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Aug 30, 2024
Registry last updated
Feb 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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