Association Between Body Roundness Index and Wound Healing

Background Obesity is a significant risk factor for adverse postoperative outcomes, including impaired wound healing. This study aimed to investigate the association between the Body Roundness Index (BRI) and impaired wound healing following thoracic surgery.

Methods This study included 387 patients who underwent thoracic surgery at Tongji Hospital in Wuhan between October 2024 and January 2025. Wound healing was assessed 30 days postoperatively. Logistic regression and propensity score matching (PSM) analyses were performed to evaluate the relationship between BRI and impaired wound healing, with subgroup analyses conducted to further explore this association.

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Key information

Conditions

Thoracic Surgery BMI Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms Visceral Fat Wound Healing

Age range

20 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Tongji Medical College of HUST Tongji Medical College Tongji Hospital

Wuhan, Hubei, 430000, China

About this study

This prospective cohort study collected clinical data from patients undergoing thoracic surgery at Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, between October 1, 2024, and January 30, 2025. Initial enrollment included 422 patients, with 387 participants retained after data cleaning (Figure 1). The primary objective was to evaluate the association between BRI and impaired postoperative wound healing through multivariable logistic regression, propensity score matching (PSM), and subgroup analyses.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

：

Patients who underwent surgical treatment in the Department of Thoracic Surgery at Tongji Hospital;
Complete clinical data and diagnostic test results available;
Postoperative follow-up conducted regularly in accordance with medical advice, with comprehensive follow-up records；

Exclusion criteria

Without surgery or transferred to other departments；
Missing basic information；
Failure to review on time or refusal to follow up；
Additional surgeries within 30 days of discharge from the hospital；

Treatment and study plan

Primary outcomes

Wound healing

Time frame: From the day of surgery to 30 days postoperatively

Determine the presence of impaired wound healing based on the definitions and guidelines for wound assessment and evaluation of healing.

Sponsors and collaborators

Lead sponsor

Zhao bo

Other

Registry information

Official study title

Association Between Body Roundness Index and Wound Healing Post-Thoracic Surgery: A Prospective Study

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2025
First posted: Jul 15, 2025
Registry last updated: Jul 15, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed