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NCT Number: NCT06730711

Association Between Blood Pressure and Risk of PSCI

This retrospective cohort study was designed to explore the relationship between blood pressure and cognitive impairment after stroke

Recruiting

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Key information

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China

Location status: Recruiting

Location contact

Defei Chen

CONTACT

[email protected]

+8617347917488

About this study

Patients who have been followed up for more than 3 months after stroke will be included in the study. Basic data of patients and factors that may be related to cognitive impairment will be collected, and the relationship between blood pressure and cognitive impairment after stroke will be explored by univariate regression analysis and multivariate regression analysis. Univariate logistic regression model and multivariate logistic regression model were used to explore the relationship between blood pressure level and the risk of cognitive impairment after stroke, and the effect of blood pressure level and cognitive impairment sub-line in different patients was evaluated by subgroup analysis.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient diagnosed with stroke by CT or MRI,
  • Patients completed the MMSE scale at least once during hospitalization
  • The follow-up time was more than three months after the stroke occurred;

Exclusion criteria

  • Patients with incomplete data, follow-up time less than three months after the stroke occurred less than 3 months,
  • Patients with pre-existing cognitive impairment before stroke according to their medical records,
  • patients failed to complete MMSE assessment because of aphasia or any other reasons,
  • Patients combined with malignant tumors, patients combined with psychiatric disorders.

Treatment and study plan

Primary outcomes

  1. Mental State Examination Scale (MMSE)

    Time frame: Mini-Mental State Examination (MMSE) assessment will be completeed at 3 monthes after stroke

    Global cognitive function assessment. Easy to use and one of the most used scales to screen person with cognitive impairment in the world. The minimum and maximum values range from 0 to 30. Higher score means better cognition level.

Study contacts

Contact information is provided by the study sponsor or research team.

Defei Chen

CONTACT

[email protected]

+8615188017034

Dingqun Bai

CONTACT

[email protected]

13808380876

Sponsors and collaborators

Lead sponsor

First Affiliated Hospital of Chongqing Medical University

Other

Registry information

Official study title

Association Between Blood Pressure and the Risk of Post-stroke Cognitive Impairment: a Retrospective Cohort Study

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Dec 12, 2024
Registry last updated
Dec 12, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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