Assist Control Versus Pressure Support Modes for Domiciliary Noninvasive Ventilation in Chronic Respiratory Failure

Noninvasive ventilation is a therapeutic option in some patients with chronic respiratory failure. Patients usually ventilate during nightime with a domiciliary ventilator either in assist control or in pressure support mode.

The aim of this study is to compare the clinical efficacy and the tolerance of assist control and pressure support modes during domiciliary noninvasive ventilation in patients with chronic respiratory failure.

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Key information

Conditions

Chronic Respiratory Failure

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Chronic respiratory failure
Clinical symptoms of chronic alveolar hypoventilation
PaCO2 ≥ 45 mmHg in case of restrictive pulmonary disorder or PaCO2 ≥ 55 mmHg in case or obstructive pulmonary disorder

Exclusion criteria

Clinical exacerbation during the three previous weeks
Previous treatment by domiciliary non invasive ventilation
Previous treatment by non invasive ventilation for acute respiratory failure during the 3 previous months
Bronchiectasis
Duchenne muscular dystrophy
Amyotrophic lateral sclerosis

Treatment and study plan

respiratory settings

Procedure

Primary outcomes

PaO2

Time frame: months

Blood gases response to ventilation

Sponsors and collaborators

Lead sponsor

Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche

Other

Registry information

Official study title

Assist Control Versus Pressure Support Modes for Domiciliary Noninvasive Ventilation

Important dates

Study start: 2006
Primary completion: 2009
Study completion: 2009
First posted: Sep 19, 2005
Registry last updated: Feb 17, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed