Assessment of Zinc Absorption From a Phytic Acid Rich Complementary Food

Assessment of zinc absorption from a phytic acid rich complementary food, consumed by young children immediately after the addition of the enzyme phytase. A randomized single blind study

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Key information

Conditions

Bioavailability

Age range

12 month–24 month

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU-Yalgado Ouédraogo, Service Pédiatrie

Ouagadougou, Burkina Faso

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

12-24 month old
Male of female
Height and weight between -2.0 SD and +2.0 SD with respect to WHO child growth standards.
No mineral and vitamin supplements 2 weeks prior to the study and during the whole duration of the study

Exclusion criteria

Body temperature ≥ 37.5°C
Hemoglobin ≤ 7g/dL
Positive RDT test
Any metabolic, gastrointestinal or chronic disease (according to the statement of the subject's parent) known chronic diseases at the gastrointestinal tract)
Long term mediation (that may affect zinc metabolism) during the whole study to interact with zinc metabolism (such as kidney diseases or

Treatment and study plan

Primary outcomes

Fractional absorption of zinc

Time frame: 33 days

Fractional absorption of zinc is estimated by using the double isotope tracer ratio technique by administering 67Zn as oral and 70Zn as intravenous stable isotopes.The urinary enrichment with both isotopes is measured in a spot urine sample by inductively coupled plasma mass spectrometry.

Sponsors and collaborators

Lead sponsor

Swiss Federal Institute of Technology

Other

Registry information

Official study title

Assessment of Zinc Absorption From a Phytic Acid Rich Complementary Food, Consumed by Young Children Immediately After the Addition of the Enzyme Phytase. A Randomized Single Blind Study

Important dates

Study start: 2011
Primary completion: 2012
Study completion: 2012
First posted: Jan 10, 2012
Registry last updated: Nov 28, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed