Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07035574

Assessment of Wear and Muscular Efficiency of 3D Printed Versus Conventional Denture Teeth: A Cross-Over In Vivo Study

This study aims to evaluate the wear resistance and muscular efficiency of denture teeth fabricated using two different methods: 3D printing and conventional techniques. The research is designed as a crossover in vivo study, where completely edentulous patients will receive both types of dentures sequentially. The primary outcome is the amount of wear observed in the denture teeth over time, while the secondary outcome is the muscular efficiency measured using electromyography (EMG). The study seeks to determine whether 3D printed denture teeth offer advantages in durability and functionality compared to conventionally fabricated denture teeth. Results from this study may provide valuable insights into improving the quality and comfort of dentures for edentulous patients.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Age range

21 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Complete dentures are a common treatment option for edentulous patients, providing essential functionality and aesthetics. With advancements in digital dentistry, 3D printing has emerged as a promising technique for fabricating denture teeth, offering potential benefits such as customization, faster production, and improved material properties. However, the long-term performance of 3D printed denture teeth compared to conventionally fabricated teeth remains under investigation.

This study is designed to assess two critical aspects of denture teeth performance: wear resistance and muscular efficiency. Wear resistance refers to the ability of denture teeth to withstand forces during chewing without significant degradation, while muscular efficiency evaluates how effectively the jaw muscles function with the dentures during activities like chewing and speaking.

The study will recruit completely edentulous patients aged 21-70 years from the Prosthodontics Department at Cairo University. Participants will receive two sets of complete dentures: one fabricated using conventional techniques and the other using 3D printing. The crossover design allows for direct comparison within the same group of patients, minimizing individual variability.

Primary impressions will be taken, followed by the fabrication of dentures using standardized protocols. The amount of wear will be measured by scanning the denture teeth at delivery and after three months of use. Muscular efficiency will be assessed using electromyography (EMG) to measure bite force at delivery and after three months.

This study is self-funded and conducted under the supervision of the Prosthodontics Department at Cairo University. Ethical approval has been obtained, and all participants will provide informed consent. The findings of this study are expected to contribute to the advancement of prosthodontic practices, offering evidence-based recommendations for the use of 3D printed denture teeth in clinical settings.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Completely edentulous patients. Aged 21-70 years old. Able to read and sign the informed consent document. Class Ι maxilla-mandibular relationship. Free from temporomandibular disorders. Free from systemic diseases that could affect neuromuscular behaviors or muscular activities.

Edentulous condition falls within Class I and II cases based on the Prosthodontic Diagnostic Index (PDI) classification system for complete edentulism.

Exclusion criteria

Presence of major medical problems or severe chronic diseases. Poor residual ridge anatomy. Any intra-oral soft or hard tissue abnormalities. Flat, flabby, or knife-edge ridge anatomy.

-

Treatment and study plan

Conventional Denture Teeth

Other

Complete dentures fabricated using conventional techniques with prefabricated acrylic denture teeth.

3D Printed Denture Teeth

Other

Complete dentures fabricated using additive manufacturing techniques with advanced resin materials.

Primary outcomes

  1. Amount of Wear

    Time frame: 6 months

    The amount of wear observed in denture teeth fabricated using conventional techniques versus 3D printing technology. Denture teeth will be scanned at delivery and after 3 months of use, and the wear will be quantified by comparing the scans.

Secondary outcomes

  1. Muscular Efficiency

    Time frame: 6months

    Muscular efficiency will be assessed by measuring maximum bite force using electromyography (EMG) at delivery and after 3 months of use. The variation in bite force between conventional and 3D printed denture teeth will be analyzed.

Study contacts

Contact information is provided by the study sponsor or research team.

tuqa s madhi, B.D.S.

CONTACT

[email protected]

+20 1221905983

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Assessment of the Amount of Wear and Muscular Efficiency of 3D Printed Denture Teeth Versus Conventionally Fabricated Denture Teeth: A Cross-Over In Vivo Study

Acronym: 3D-DENTURE

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Jun 25, 2025
Registry last updated
Jun 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.