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OpenTrials
Completed

NCT Number: NCT02234336

Assessment of Wall Thickness in Hypertrophic Cardiomyopathy

Assessment of wall thickness in hypertrophic cardiomyopathy (HCM) is of diagnostic and prognostic importance given its known association with sudden cardiac death. However, data regarding comparison of imaging modalities for this key measurement is lacking. This study seeks to compare assessment of maximum wall thickness between clinically indicated echocardiography (with and without contrast) and clinically indicated cardiac magnetic resonance imaging.

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Key information

Conditions

Hypertrophic Cardiomyopathy Aortic Stenosis, Subvalvular Aortic Valve Disease Aortic Valve Stenosis Cardiomyopathies Cardiomyopathy, Hypertrophic Cardiovascular Diseases Heart Diseases Heart Valve Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

About this study

Patients receiving clinically indicated echocardiograms and cardiac magnetic resonance imaging at Mayo Clinic will be eligible.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Clinically and echocardiographically defined hypertrophic cardiomyopathy.
  • Clinically indicated transthoracic echocardiography as part of the medical evaluation.
  • No contradiction to administration of ultrasonic echocardiography contrast.
  • Planned clinically indicated cardiac magnetic resonance imaging as part of medical evaluation.
  • No contraindication to cardiac magnetic resonance imaging (such as cochlear implants, central nervous system aneurysm clips and other implanted medical devices).
  • Age 18 years and older

Exclusion criteria

  • Insufficient image quality for determination of maximal wall thickness.

Treatment and study plan

Noncontrast echocardiography

Procedure

Contrast Echocardiography

Procedure

Cardiac Magnetic Resonance Imaging

Procedure

Primary outcomes

  1. Left Ventricular Wall Thickness

    Time frame: approximately 1 week after enrollment

    All subjects will undergo noncontrast echocardiography, contrast echocardiography and cardiac MRI.

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Collaborators

  • GE Healthcare

Registry information

Important dates

Study start
2014
Primary completion
2017
Study completion
2017
First posted
Sep 9, 2014
Registry last updated
Feb 5, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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