Assessment of the Benefits of Adapted Physical Activity in Pediatric Hemodialysis Patients

Children, adolescents, and young adults undergoing pediatric hemodialysis often experience functional limitations in daily life. Their level of physical activity is generally lower than that of healthy peers of the same age, due to the lack of sports programs adapted both to their medical conditions and to the constraints of dialysis (notably, having to remain in bed for several hours, several times a week). These limitations affect not only their cardiovascular function but also their quality of life.

Through the implementation of an Adapted Physical Activity (APA) program for dialysis patients, we aim to assess the potential benefits of this approach on muscle strength, functional abilities, cardiovascular health, and quality of life

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Key information

Conditions

Hemodialysis Behavior Motor Activity

Age range

5 year–20 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patient requiring hemodialysis sessions for end-stage renal disease
Patient aged between 5 and 20 years
Patient followed in the pediatric nephrology department at hospital Lyon (HFME : Hôpital Femme Mère Enfant)
Adult patient or parents/legal guardians informed about the study and having provided written consent for participation
Patient covered by a social security

Exclusion criteria

Medical or surgical contraindications to adapted physical activity.

Persons deprived of liberty by judicial or administrative decision.
Persons undergoing psychiatric care.
Persons admitted to a healthcare or social facility for reasons other than research participation.
Adults under legal protection measures (curators)
Persons not affiliated with a social security scheme or beneficiaries of a similar system
Pregnant women.

Treatment and study plan

adapted physical activity

Other

adapted physical activity for 30 to 45 minutes twice per week

Primary outcomes

mass-to-muscle mass ratio between M0 and M6

Time frame: Between baseline (M0) and month 6 (M6)

Change in the mass-to-muscle mass ratio between M0 and M6, measured at the end of the hemodialysis session using bioelectrical impedance analysis.

Study contacts

Contact information is provided by the study sponsor or research team.

Melodie MOSCA, MD

CONTACT

[email protected]

04 27 85 67 49 ext. +33

Sacha FLAMMIER

CONTACT

[email protected]

04 72 68 13 49 ext. +33

Sponsors and collaborators

Lead sponsor

Hospices Civils de Lyon

Other

Registry information

Official study title

Assessment of the Benefits of Adapted Physical Activity in Pediatric Hemodialysis Patients-DIALAPA Study

Acronym: DIALAPA

Important dates

Study start: 2025
Primary completion: 2029
Study completion: 2029
First posted: Aug 12, 2025
Registry last updated: Aug 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed