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Completed

NCT Number: NCT07108842

Assessment of Pain Using Two Different Irrigation Systems After Root Canal Treatment

assessment of pain using two different irrigation systems after root canal treatment

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Key information

Conditions

Pulpal Inflammation

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Dental hospial, Hitec-IMS

Rawalpindi, Punjab Province, Pakistan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Single rooted teeth (Anterior or posterior)
  • Teeth with symptomatic irreversible pulpitis with acute apical periodontitis
  • Age group 18-65 years

Exclusion criteria

  • Non-restorable teeth, teeth with acute or chronic apical abcess, teeth with internal/external root resorption
  • Teeth with anatomical difficulties like open apices, calcified canals, dilacerations
  • Patients that had any serious medical illness or with systemic disorders
  • Previous root canal treatment
  • Periodontally compromised teeth
  • Presence of sinus tract

Treatment and study plan

Conventional Needle Irrigation

Procedure

Patients in this arm will receive traditional syringe and needle irrigation using a 30-gauge side-vented needle. 2.5% sodium hypochlorite will be used as the irrigant, delivered 1-2 mm short of working length intermittently during root canal instrumentation. No activation device will be used.

Other names: Sonic Irrigation with EndoActivator (Experimental Group)

Conventional Needle Irrigation (Control Group)

Device

Patients in this arm will receive traditional syringe and needle irrigation using a 30-gauge side-vented needle. 2.5% sodium hypochlorite will be used as the irrigant, delivered 1-2 mm short of working length intermittently during root canal instrumentation. No activation device will be used.

Other names: use of endoactivator

endoactivator

Device

in group 2 irrigation done with endoactivator

Irrigation Solution

Device

irrigation protocol done with disposable syringe

Sonic Irrigation with EndoActivator (Experimental Group)

Device

Patients in this arm will receive sonic activation of the irrigant using the EndoActivator device during root canal treatment. After initial instrumentation and irrigation with 2.5% sodium hypochlorite, the irrigant will be activated using a medium-sized (25/04) EndoActivator tip for 30 seconds per canal at a sonic frequency (~6000 cycles/min), to enhance cleaning and irrigant penetration.

Primary outcomes

  1. Postoperative Pain

    Time frame: Pain scores will be recorded at 6 hours, 24 hours, and 48 hours after completion of root canal treatment.

    Assessment of postoperative pain intensity using a Visual Analog Scale (VAS) ranging from 0 (no pain) to 10 (worst possible pain).

Secondary outcomes

  1. Analgesic Consumption

    Time frame: 0 to 48 hours after treatment

    Number of analgesic tablets (e.g., ibuprofen/paracetamol) consumed by patients within the first 48 hours post-treatment.

Sponsors and collaborators

Lead sponsor

HITEC-Institute of Medical Sciences

Other

Registry information

Official study title

Evaluation of Postoperative Pain After Using Two Different Irrigation Systems During Endodontic Treatment

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Aug 7, 2025
Registry last updated
Aug 7, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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