future university in Egypt
Cairo, New Cairo, 11835, Egypt
Location status: Recruiting
NCT Number: NCT06613932
Clinical and Radiographic Assessment of L-PRF, Nanohydroxyapatite material combined with L-PRF scaffold in Vital pulp Therapy. Treatments in Mandibular First Molars with Closed Apices, Randomized Controlled Trial.
Interested in participating?
Request Info15 year–30 year
All sexes
Interventional
Not applicable
Cairo, New Cairo, 11835, Egypt
Location status: Recruiting
pulpotomy by using 3 materials. The first group(control group ) uses hydroxyapatite material as a pulpotomy agent, and the second group uses L-PRF as a pulpotomy agent. the third group uses combined material (L-PRF = Nano hydroxyapatite )as a pulpotomy agent .. then assesses the clinical and radiographic result of the 2 interventions group with control group
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Patients should be free from any systemic disease. Patients of either gender aged from 15-30. Patients will agree to the consent and will commit to a follow-up period. Soft tissues around the tooth are normal with no swelling or sinus tract. The tooth is restorable tooth has signs and symptoms of irreversible pulpitis of the mature root The tooth doesn't contain any internal or external resorption or periapical lesions.
The tooth should give a positive response to the cold test.
Exclusion criteria
Pregnant and lactating females. Patients with Mental disturbance. Patients who could/would not participate in a 6-month follow-up. A tooth with immature roots. Patients with necrotic pulp.• tooth with periapical lesions or infections. Soft tissue having fistula or swelling Homoeostasis after 10 minutes can not be controlled after total pulpotomy
removal of the coronal pulp tissue and preservation of the radicular portion to ensure continuation of growth and vitality of tooth structure
Other names: vital pulp therapy
Time frame: 6, 12, 24, 72hours and 7 days after treatment
Pain evaluations were conducted preoperatively with numerical rating scale ( a verbal or writing determination of a pain level on a scale from 0 to 10, in which 0 represents no pain and 10 represents excruciating pain .
Time frame: 12 months post operative
evaluating the thickness of dentine bridge formed after the procedure by comparing immediate post operative CBCT with the one year follow up scans
Contact information is provided by the study sponsor or research team.
nada A metwally, master
CONTACT
01122289353 ext. +02
toka A metwally, bachelor's
CONTACT
01068681660 ext. +02
Future University in Egypt
Other
Clinical and Radiographic Assessment of L-PRF, Nanohydroxyapatite Material Combined With L-PRF Scaffold in Vital Pulp Therapy. Treatments in Mandibular First Molars With Closed Apices "Randomized Controlled Trial"
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07163975
Diabetes Mellitus, Diabetes Mellitus, Type 2
Rohtak, Haryana, India
View Trial DetailsNCT06843525
Apical Periodontitis, Dental Pulp Diseases
Newark, New Jersey, United States
View Trial DetailsNCT06918639
Irreversible Pulpitis, Pulpotomy of Permanent Molars
Alcorcón, Madrid, Spain
View Trial DetailsNCT06844448
Dental Caries Extending to Pulp, Dental Pulp Diseases
Budapest, Hungary
View Trial Details