Skip to main content
OpenTrials
Recruiting

NCT Number: NCT06613932

Assessment of L-PRF, Nanohydroxyapatite Combined With L-PRF Using Pulpotomy in Mature Mandibular First Molars

Clinical and Radiographic Assessment of L-PRF, Nanohydroxyapatite material combined with L-PRF scaffold in Vital pulp Therapy. Treatments in Mandibular First Molars with Closed Apices, Randomized Controlled Trial.

Recruiting

Interested in participating?

Request Info

Key information

Age range

15 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

future university in Egypt

Cairo, New Cairo, 11835, Egypt

Location status: Recruiting

Location contact

nada A metwally, master

CONTACT

[email protected]

01122289353 ext. +02

About this study

pulpotomy by using 3 materials. The first group(control group ) uses hydroxyapatite material as a pulpotomy agent, and the second group uses L-PRF as a pulpotomy agent. the third group uses combined material (L-PRF = Nano hydroxyapatite )as a pulpotomy agent .. then assesses the clinical and radiographic result of the 2 interventions group with control group

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients should be free from any systemic disease. Patients of either gender aged from 15-30. Patients will agree to the consent and will commit to a follow-up period. Soft tissues around the tooth are normal with no swelling or sinus tract. The tooth is restorable tooth has signs and symptoms of irreversible pulpitis of the mature root The tooth doesn't contain any internal or external resorption or periapical lesions.

The tooth should give a positive response to the cold test.

Exclusion criteria

Pregnant and lactating females. Patients with Mental disturbance. Patients who could/would not participate in a 6-month follow-up. A tooth with immature roots. Patients with necrotic pulp.• tooth with periapical lesions or infections. Soft tissue having fistula or swelling Homoeostasis after 10 minutes can not be controlled after total pulpotomy

Treatment and study plan

Pulpotomy

Procedure

removal of the coronal pulp tissue and preservation of the radicular portion to ensure continuation of growth and vitality of tooth structure

Other names: vital pulp therapy

Primary outcomes

  1. post operative Pain assessment

    Time frame: 6, 12, 24, 72hours and 7 days after treatment

    Pain evaluations were conducted preoperatively with numerical rating scale ( a verbal or writing determination of a pain level on a scale from 0 to 10, in which 0 represents no pain and 10 represents excruciating pain .

Secondary outcomes

  1. Dentine bridge formation

    Time frame: 12 months post operative

    evaluating the thickness of dentine bridge formed after the procedure by comparing immediate post operative CBCT with the one year follow up scans

Study contacts

Contact information is provided by the study sponsor or research team.

nada A metwally, master

CONTACT

[email protected]

01122289353 ext. +02

toka A metwally, bachelor's

CONTACT

01068681660 ext. +02

Sponsors and collaborators

Lead sponsor

Future University in Egypt

Other

Registry information

Official study title

Clinical and Radiographic Assessment of L-PRF, Nanohydroxyapatite Material Combined With L-PRF Scaffold in Vital Pulp Therapy. Treatments in Mandibular First Molars With Closed Apices "Randomized Controlled Trial"

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Sep 26, 2024
Registry last updated
Sep 26, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.