Assessment of Intracellular Cytokines and Markers in Cells (Phase 3)

Inclusion criteria

• Potential subjects must satisfy all of the following criteria to be enrolled in the study:

• They are of legal age (18 years) and capacity to volunteer.
• They understand their rights as a research subject and are willing and able to sign a Statement of Informed Consent.
• They are willing and able to follow the protocol.
• They agree not to participate in other clinical research for the duration of this study.

Exclusion criteria

• Potential subjects who meet any of the following criteria will be excluded from participating in the study:

• They have had cataract surgery.
• They have had corneal refractive surgery.
• They have any corneal distortion resulting from previous hard or rigid lens wear or have keratoconus.
• They are pregnant or breast-feeding.
• They have any infectious disease (e.g. hepatitis) or any immunosuppressive disease (e.g. HIV) or a history or anaphylaxis or severe allergic reactions.
• They have taken part in any other contact lens or care solution clinical trial research, within two weeks prior to starting this study.
• They are currently regularly (once per day or more) using oral or inhaled steroids or anti-inflammatory medications.
• They are using any topical medications such as eye drops or ointments.
• They are a current (i.e. within the last three months) contact lens wearer (wearing a lens in one or both eyes).
• History of allergic reaction to sodium fluorescein or topical anesthetic.
• They have Grade 3 or greater of any of the following ocular surface signs: corneal edema, corneal vascularization, corneal staining (white light evaluation), tarsal conjunctival changes or any other abnormality which would normally contraindicate contact lens wear.
• Any active ocular infection or inflammation.