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Completed

NCT Number: NCT04431921

Assessment of Functional Capacity, Pain, Cognitive and Respiratory Functions in Lung Cancer Survivors

Serious side effects occurs with disease and treatments in survival after lung cancer. For this reason, functional capacity, cognitive status, pain perception and respiratory functions may be affected in lung cancer. The purpose of this study was to evaluate respiratory function, respiratory muscle strength and endurance, functional capacity, pain, cognitive status level, and physical activity in lung cancer patients and compare with the findings of healthy subjects

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Key information

Conditions

Lung Neoplasm Cognition Disorders Cognitive Dysfunction Lung Diseases Lung Neoplasms Mental Disorders Neoplasms Neoplasms by Site Neurocognitive Disorders Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Respiratory Tract Diseases Respiratory Tract Neoplasms Signs and Symptoms Survivorship Thoracic Neoplasms

Age range

45 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Hacettepe University

Ankara, Turkey (Türkiye)

About this study

This study was participated lung cancer patients survivors. Patients' pulmonary function test, functional capacity, respiratory muscle strength and endurance, pain and cognitive status was assessed and recorded.

Pulmonary function testing (PFT), mouth pressure measurement (MIP- maximal inspiratory pressure and MEP- maximal expiratory pressure), respiratory muscle endurance test, six minute walk test (6MWT) and pain threshold and tolerance test were used. In addition to physiological measurements, the Montreal Cognitive Assessment (MoCA) scale was used to evaluate cognitive status, the International Physical Activity Questionnaire (IPAQ) was used to determine the level of physical activity.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Cooperation
  • lung cancer patients who had a stable condition

Exclusion criteria

  • Active cancer treatments
  • Brain metastasis story
  • Any orthopedic disease impairs walking, balance

Treatment and study plan

Functional capacity

Diagnostic Test

Six minute walk test used assessment of functional capacity. For respiratory function mouth pressures, for cognitive functions MoCA scale and for pain assessment pain threshold and tolerance test assessed.

Other names: Exercise capacity

Primary outcomes

  1. Functional capacity

    Time frame: 15 minutes

    Six minute walk test: Distance walked in six minute was recorded

Secondary outcomes

  1. Respiratory muscle strength assessment

    Time frame: 10 minutes

    Respiratory muscle strength was evaluated by measuring maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP).

  2. Respiratory muscle endurance

    Time frame: 10 minutes

    Pressure time unit: A constant load test was used to evaluate respiratory muscle endurance. Using a PowerBreathe device (HaB International Ltd., Southam, UK), the participants were asked to breathe maintaining a constant threshold (60% of MIP) until task failure, and the test duration was recorded. Results were obtained by multiplying the set pressure by the test duration

  3. Pulmonary functions test

    Time frame: 15 minutes

    pulmonary functions assessment via spirometry

  4. Cognition using MoCA-Test

    Time frame: 10 minutes

    Cognitive function was evaluated with the secreening tool the Montreal Cognitive Assessment (MoCA). The MoCA is a 30-point screening tool. Higher scores mean a better outcome.

  5. Pressure pain threshold assessment

    Time frame: 15 minute

    Pressure pain threshold was evaluated via algometer. The pressure at which the individual first reported pain was recorded.

  6. Pressure pain tolerance assessment

    Time frame: 15 minute

    Pressure pain tolerance test was evaluated via algometer.The pressure at which the individual last pressure point at which they could endure the pain was recorded.

  7. Physical activity level

    Time frame: 5 minutes

    International Physical Activity Questionnaire-Short Form

Sponsors and collaborators

Lead sponsor

Hacettepe University

Other

Registry information

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Jun 16, 2020
Registry last updated
Jun 16, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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