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NCT Number: NCT04921020

Assessment of Eyelid Topology and Kinetics Based on Deep Learning Method

This study plans to assess eyelid topology (such as margin reflex distance, eyelid contour, and corneal exposure area) and blinking (such as frequency, velocity, and duration), using deep learning method to automatically extract eyelid topological features, and to predict subtypes of levator function, using deep learning method to extract blinking features, in order to provide new ideas and means to assess eyelid topology and kinetics.

Recruiting

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Key information

Conditions

Eyelid Diseases Eye Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • normal volunteers without eyelid diseases
  • patients with blepharoptosis
  • patients with blepharospasm
  • patients with dry eye disease
  • patients with Graves' disease

Exclusion criteria

variable ptosis (e.g., myasthenia gravis), entropion, ectropion, enophthalmos, exophthalmos, strabismus, and abnormalities of pupil

Treatment and study plan

Photography

Other

Facial photographs and blinking videos are taken

Primary outcomes

  1. one-dimensional parameters of eyelid topology

    Time frame: through study completion, 5 years

    Palpebral fissure length [Margin reflex distance 1, Margin reflex distance 2], Lid length [Upper lid length, Lower lid length], Multiple mid-pupil lid distances

  2. two-dimensional parameters of eyelid topology

    Time frame: through study completion, 5 years

    Palpebral fissure area [Medial area, Corneal area, Lateral area]

  3. subtypes of levator function

    Time frame: through study completion, 5 years

    Levator function is classified into three categories: good, fair and poor

Study contacts

Contact information is provided by the study sponsor or research team.

Juan Ye

CONTACT

[email protected]

+86-571-87783897

Lixia Lou

CONTACT

[email protected]

+86-15088681589

Sponsors and collaborators

Lead sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Other

Registry information

Official study title

Department of Ophthalmology

Important dates

Study start
2020
Primary completion
2025
Study completion
2026
First posted
Jun 10, 2021
Registry last updated
Jun 10, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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