Assessment of Early Pregnancy MAB Completion

This is a prospective study to evaluate if successful completion of a medication abortion in patients with very early pregnancy can be detected with a urine pregnancy test at 2 weeks instead of 4 weeks. Additionally, the resolution of pregnancy symptoms in these patients will be characterized. Enrolled participants will take take weekly pregnancy tests and complete weekly questionnaires on their pregnancy symptoms for 4 weeks after their medication abortion.

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This study is active but is not currently recruiting participants.

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Key information

Conditions

Pregnancy Abortion Early

Sex eligibility

Female

Study type

Observational

Primary location

Carafem, Atlanta, Georgia, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Pregnant person with early pregnancy ≤42 days
Eligible and consented to a medication abortion
Have access to receiving text messages and the internet
Able to read and understand English

Exclusion criteria

Privacy or safety concerns about filling out the surveys

Treatment and study plan

Weekly high-sensitivity urine pregnancy tests

Diagnostic Test

Participants will take a high-sensitivity urine pregnancy test at home weekly for up to 4 weeks compared to the taking just one home urine pregnancy test at 4-5 weeks. Participants will also complete short weekly questionnaires on their pregnancy symptoms and follow-up care.

Primary outcomes

Proportion of participants with negative high-sensitivity urine pregnancy test at 2 weeks

Time frame: From time of taking Mifepristone to negative pregnancy test or 4-5 weeks of questionnaires

To estimate the proportion of negative high-sensitivity urine pregnancy tests in participants with very early pregnancy and a complete abortion at 2 weeks after taking Mifepristone and compare this proportion to the proportion of negative high-sensitivity urine pregnancy tests in participants with very early pregnancy and a complete abortion at 4 weeks

Secondary outcomes

Time to resolution of pregnancy symptoms

Time frame: From time of taking Mifepristone to negative pregnancy test or 4-5 weeks of questionnaires

To compare the timing of pregnancy symptom resolution per patient report on weekly questionnaires with the timing of a negative high-sensitivity urine pregnancy test result

Sponsors and collaborators

Lead sponsor

University of Washington

Other

Registry information

Official study title

Assessing Completion of Medication Abortion for Very Early Pregnancies

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2026
First posted: Mar 25, 2025
Registry last updated: May 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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