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Active, Not Recruiting

NCT Number: NCT05525741

Assessment of Circulating Fubctional Mitochondrias in Vitiligo Patients

To compare the level of circulating functional mitochondria in the serum of vitiligo patients as compared to controls

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Skin and Connective Tissue Diseases

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

CHU de Nice - Hôpital de l'Archet

Nice, Alpes-maritimes, 06200, France

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with non segmental vitiligo,
  • atopic dermatitis, psoriais, alopecia areata,
  • 1st degree relative of vitiligo patients.

Exclusion criteria

  • segmental or mixed vitiligo,
  • personnal history of other autoimmune disorders,
  • oral use of antioxidant,
  • pregant women

Treatment and study plan

Non segmental vitiligo

Other

The subjects will be selected from among those presenting for the consultation or hospitalization of the Dermatology department of the CHU de Nice. All necessary information will be given to the subjects and a briefing note will be given to them. A reflection period will be left for the subjects to sign the informed consent, and if necessary, another appointment will be scheduled for the inclusion visit.

The Investigator:

  • Inform the subject of the goals, constraints and risks of the study and obtain written consent.
  • Conduct an examination of the subject's medical history Will verify that the subject meets all inclusion criteria and does not present any of the criteria for not including.

If the subject consents and they meet all the criteria a 20 ml blood sample will be taken.

Health Volunteers

Other

The subjects will be selected from among those presenting for the consultation or hospitalization of the Dermatology department of the CHU de Nice. The family control subjects will be recruited from the vitiligos patients coming into our department. All necessary information will be given to the subjects and a briefing note will be given to them. A reflection period will be left for the subjects to sign the informed consent, and if necessary, another appointment will be scheduled for the inclusion visit.

The Investigator:

  • Inform the subject of the goals, constraints and risks of the study and obtain written consent.
  • Conduct an examination of the subject's medical history Will verify that the subject meets all inclusion criteria and does not present any of the criteria for not including.

If the subject consents and they meet all the criteria a 20 ml blood sample will be taken.

Primary outcomes

  1. Total number of circulating functionnal mitochondria (CFM) in the plasma

    Time frame: at baseline

    Level of CFM in vitiligo serum as compared to controls

Secondary outcomes

  1. measuring the functionality of circulating mitochondria

    Time frame: At baseline

    Functional analysis of CFM in vitiligo patients as compared to controls analyzed by MFI Mito Tracker

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nice

Other

Registry information

Official study title

Assessment of Circulating Fubctional Mitochondrias in Vitiligo Patients as Compared to Controls

Acronym: MFC

Important dates

Study start
2022
Primary completion
2023
Study completion
2025
First posted
Sep 2, 2022
Registry last updated
Dec 4, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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